Interest in the function of ataxia-telangiectasia-mutated protein (ATM) is extensively growing
as evidenced by preclinical studies that continuously link ATM with new intracellular …

The capacity to guarantee the proper excitatory/inhibitory balance is one of the most critical
steps during early development responsible for the correct brain organization, function, and …

Despite that the human autosomal recessive disease ataxia telangiectasia (AT) is a rare
pathology, interest in the function of ataxia-telangiectasia mutated protein (ATM) is …

Ataxia telangiectasia (AT) is a multisystemic disease caused by mutations in the ATM (AT
mutated) gene. It strikes before 5 years of age and leads to dysfunctions in many tissues …

Ataxia telangiectasia is a multisystemic disorder that includes a devastating
neurodegeneration phenotype. The ATM (ataxia-telangiectasia mutated) protein is well …

Neural degeneration is one of the clinical manifestations of ataxia–telangiectasia, a disorder
caused by mutations in the Atm protein kinase gene. However, neural degeneration was not …

The autosomal recessive disorder Ataxia-Telangiectasia is caused by a dysfunction of the
stress response protein, ATM. In the nucleus of proliferating cells, ATM senses DNA double …

Impairment of the GABAergic system has been reported in epilepsy, autism, attention deficit
hyperactivity disorder, and schizophrenia. We recently demonstrated that ataxia …

Ataxia–Telangiectasia Mutated (ATM) is a serine/threonine protein kinase principally known
to orchestrate DNA repair processes upon DNA double-strand breaks (DSBs). Mutations in …

Ataxia‐telangiectasia (A‐T) is characterized by neuronal degeneration, cancer, diabetes,
immune deficiency, and increased sensitivity to ionizing radiation. A‐T is attributed to the …