Epidemiology and clinical burden of acute myeloid leukemia

A Redaelli, JM Lee, JM Stephens… - Expert review of …, 2003 - Taylor & Francis
Acute myeloid leukemia is the most common type of leukemia in adults, yet it continues to
have the lowest survival rate of all leukemias. Prognosis for the elderly in particular …

A review of FDA-approved acute myeloid leukemia therapies beyond '7+ 3'

A Bazinet, S Assouline - Expert review of hematology, 2021 - Taylor & Francis
Introduction: The standard anthracycline and cytarabine-based chemotherapy for acute
myeloid leukemia (AML) has changed relatively little since the 1970s and produces …

Acute myeloid leukemia: focus on novel therapeutic strategies

TL Lin, MY Levy - Clinical Medicine Insights: Oncology, 2012 - journals.sagepub.com
Acute myeloid leukemia (AML) is a heterogeneous disease with variable clinical outcomes.
Cytogenetic analysis reveals which patients may have favorable risk disease, but 5-year …

New treatment options for acute myeloid leukemia in 2019

M Cerrano, R Itzykson - Current oncology reports, 2019 - Springer
Abstract Purpose of Review The extensive genomic characterization of acute myeloid
leukemia (AML) led to the identification of a vast number of potential therapeutic targets. We …

New drugs in acute myeloid leukemia

E Estey - Seminars in oncology, 2008 - Elsevier
Standard treatment of acute myeloid leukemia (AML) results in a median survival of
approximately 1 year. Together with increasing understanding of the biology of AML, this …

New and emerging therapies for acute myeloid leukaemia

JR Davis, DJ Benjamin… - Journal of Investigative …, 2018 - journals.sagepub.com
The treatment of acute myeloid leukemia (AML) has remained relatively unchanged for the
past 3–4 decades with generally poor outcomes, especially in elderly populations unfit for …

Novel agents and regimens in acute myeloid leukemia: latest updates from 2022 ASH Annual Meeting

KW DiNardo, TW LeBlanc, H Chen - Journal of hematology & oncology, 2023 - Springer
Developments in investigational agents and novel regimens in acute myeloid leukemia
(AML) were reported in the 2022 American Society of Hematology (ASH) annual meeting …

[HTML][HTML] Treatment of older patients with acute myeloid leukemia (AML): revised Canadian consensus guidelines

JM Brandwein, N Zhu, R Kumar, B Leber… - American journal of …, 2017 - ncbi.nlm.nih.gov
The treatment of acute myeloid leukemia (AML) in older patients is undergoing rapid
changes, with a number of important publications in the past five years. Because of this, a …

Therapeutic advances in acute myeloid leukemia

A Burnett, M Wetzler, B Löwenberg - Journal of clinical oncology, 2011 - ascopubs.org
The choice of treatment approach and outcome in acute myeloid leukemia (AML) depends
on the age of the patient. In younger patients, arbitrarily defined as being younger than 60 …

Paradigm shift in the management of acute myeloid leukemia—approved options in 2023

N Premnath, YF Madanat - Cancers, 2023 - mdpi.com
Simple Summary Acute Myeloid Leukemia is the most common aggressive blood cancer in
adults. Treatment for this condition is divided into induction followed by consolidation. The …