Simultaneous determination of cocaine and metabolites in human plasma using solid phase micro-extraction fiber tips C18 and UPLC–MS/MS

LLF Lizot, ACC da Silva, MF Bastiani… - Journal of Analytical …, 2020 - academic.oup.com
The determination of cocaine (COC) and its metabolites ecgonine methyl ester (EME),
benzoylecgonine (BZE), norcocaine (NCOC) and cocaethylene (CE) in human plasma is …

Blood and plasma volumetric absorptive microsampling (VAMS) coupled to LC-MS/MS for the forensic assessment of cocaine consumption

R Mandrioli, L Mercolini, M Protti - Molecules, 2020 - mdpi.com
Reliable, feasible analytical methods are needed for forensic and anti-doping testing of
cocaine and its most important metabolites, benzoylecgonine, ecgonine methyl ester, and …

Rapid analysis of cocaine and metabolites in urine using microextraction in packed sorbent and GC/MS

T Rosado, A Gonçalves, C Margalho, M Barroso… - Analytical and …, 2017 - Springer
Cocaine is still one of the most abused drugs worldwide and, as such, it is often screened for
in driving-under-the-influence or workplace drug-testing scenarios. A large number of …

Determination of cocaine, metabolites and a crack cocaine biomarker in whole blood by liquid–liquid extraction and UHPLC–MS/MS

J Takitane, V Leyton, G Andreuccetti, H Gjerde… - Forensic science …, 2018 - Elsevier
Cocaine is a potent stimulant drug widely abused that exists in two forms: as a hydrochloride
salt and as a free base (crack). Cocaine and the inactive metabolite benzoylecgonine can …

Determination of cocaine and cocaethylene in urine by solid‐phase microextraction and gas chromatography–mass spectrometry

M Yonamine, AM Saviano - Biomedical Chromatography, 2006 - Wiley Online Library
In order to evaluate recent cocaine exposure or its coingestion with ethanol, a simple and
sensitive solid‐phase microextraction (SPME) procedure for determination of cocaine and …

Simultaneous determination of cocaine, ecgonine methyl ester, benzoylecgonine, cocaethylene and norcocaine in dried blood spots by ultra-performance liquid …

LLF Lizot, ACC da Silva, MF Bastiani, RZ Hahn… - Forensic science …, 2019 - Elsevier
Cocaine (COC) is one of the most widely abused drugs in the world and its sensitive and its
reliable measurement in blood is of great importance in the field of forensic and clinical …

An automated SPE/LC/MS/MS method for the analysis of cocaine and metabolites in whole blood

E Jagerdeo, MA Montgomery, MA LeBeau… - … of Chromatography B, 2008 - Elsevier
As laboratories are called upon to develop novel, fast, and sensitive methods, here we
present a completely automated method for the analysis of cocaine and its metabolites …

Screening of cocaine and its metabolites in human urine samples by direct analysis in real-time source coupled to time-of-flight mass spectrometry after online …

E Jagerdeo, M Abdel-Rehim - Journal of the American Society for …, 2011 - ACS Publications
Microextraction by packed sorbent (MEPS) has been evaluated for fast screening of drugs of
abuse with mass spectrometric detection. In this study, C8 (octyl-silica, useful for nonpolar to …

Solid-phase microextraction for the determination of cocaine and cocaethylene in human hair by gas chromatography–mass spectrometry

AM Bermejo, P López, I Álvarez, MJ Tabernero… - Forensic science …, 2006 - Elsevier
A method for the simultaneous determination of cocaine (COC) and cocaethylene (CE) in
human hair was developed, using solid-phase microextraction (SPME) and gas …

Pipette tip solid-phase extraction and gas chromatography–mass spectrometry for the determination of methamphetamine and amphetamine in human whole blood

C Hasegawa, T Kumazawa, XP Lee, A Marumo… - Analytical and …, 2007 - Springer
Methamphetamine and amphetamine were extracted from human whole blood samples
using pipette tip solid-phase extraction (SPE) with MonoTip C 18 tips, on which C 18 …