The plasma membrane of eukaryotic cells contains several types of lipids displaying high
biochemical variability in both their apolar moiety (eg, the acyl chain of glycerolipids) and …

The impact of cholesterol on the structure and function of membrane proteins was
recognized several decades ago, but the molecular mechanisms underlying these effects …

The molecular mechanisms that control the multiple possible modes of protein association
with membrane cholesterol are remarkably convergent. These mechanisms, which include …

Cholesterol controls the activity of a wide range of membrane receptors through specific
interactions and identifying cholesterol recognition motifs is therefore critical for …

Cholesterol is not uniformly distributed in biological membranes. One of the factors
influencing the formation of cholesterol-rich domains in membranes is the unequal lateral …

Cholesterol is a major constituent of the plasma membrane in eukaryotic cells. It regulates
the physical state of the phospholipid bilayer and is crucially involved in the formation of …

Cholesterol is a multifunctional lipid in eukaryotic cells. It regulates the physical state of the
phospholipid bilayer, is crucially involved in the formation of membrane microdomains …

As described in the literature the interaction between cholesterol and membrane proteins
can occur via direct, ligand-like and indirect mechanisms, in which cholesterol effects are …

Cholesterol is distributed nonrandomly in and between biological membranes. Despite over
two decades' investigation of these phenomena, the origin, regulation, and function of …

Membrane cholesterol is distributed asymmetrically both within the cell or within cellular
membranes. Elaboration of intracellular cholesterol trafficking, targeting and intramembrane …