[HTML][HTML] How is the norepinephrine system involved in the antiepileptic effects of vagus nerve stimulation?

A Berger, S Vespa, L Dricot, M Dumoulin… - Frontiers in …, 2021 - frontiersin.org
Vagus Nerve Stimulation (VNS) is an adjunctive treatment for patients suffering from
inoperable drug-resistant epilepsy. Although a complete understanding of the mediators …

The mechanism of action of vagus nerve stimulation for refractory epilepsy: the current status

K Vonck, K Van Laere, S Dedeurwaerdere… - Journal of clinical …, 2001 - journals.lww.com
Vagus nerve stimulation (VNS) is a neurophysiologic treatment for patients with medically or
surgically refractory epilepsy. Since the first human implant in 1989, more than 10,000 …

Vagus nerve stimulation for epilepsy: an evidence-based approach

A Cukiert - Stimulation of the Peripheral Nervous System, 2016 - karger.com
Medical treatment of seizures yields a satisfactory response in 75-80% of the patients;
resective epilepsy surgery is a therapeutic option for those patients who are refractory to …

Vagus nerve stimulation: where are we?

SC Schachter - Current opinion in neurology, 2002 - journals.lww.com
Now nearly 5 years post-approval, vagus nerve stimulation has emerged as a major non-
pharmacological treatment for epilepsy. The place of vagus nerve stimulation among …

Animal models for vagus nerve stimulation in epilepsy

M Aalbers, J Vles, S Klinkenberg, G Hoogland… - Experimental …, 2011 - Elsevier
Vagus nerve stimulation (VNS) is a moderately effective adjunctive treatment for patients
suffering from medically refractory epilepsy and is explored as a treatment option for several …

Electrical stimulation in epilepsy: vagus nerve and brain stimulation

BC Jobst - Current treatment options in neurology, 2010 - Springer
Opinion statement Vagus nerve stimulation (VNS) for epilepsy is a well established and
effective treatment for medically intractable epilepsy. VNS is indicated if resective epilepsy …

Therapeutic mechanisms of vagus nerve stimulation

TR Henry - Neurology, 2002 - AAN Enterprises
Experiments in acute and chronic animal models of epilepsy provide mechanistic insight into
the acute abortive, acute prophylactic, and chronic progressive prophylactic, anti-seizure …

Theoretical basis of vagus nerve stimulation

F Attenello, AP Amar, C Liu, MLJ Apuzzo - Stimulation of the Peripheral …, 2016 - karger.com
Despite a myriad of medical and surgical treatments for epilepsy developed over the past
few decades, a large subset of patients remains refractory to treatment. Over this time period …

[HTML][HTML] The P3 event-related potential is a biomarker for the efficacy of vagus nerve stimulation in patients with epilepsy

L De Taeye, K Vonck, M Van Bochove, P Boon… - …, 2014 - Elsevier
Currently, the mechanism of action of vagus nerve stimulation (VNS) is not fully understood,
and it is unclear which factors determine a patient's response to treatment. Recent …

[HTML][HTML] Vagus nerve stimulation for epilepsy: A review of the peripheral mechanisms

SE Krahl - Surgical neurology international, 2012 - ncbi.nlm.nih.gov
Vagus nerve stimulation (VNS) is a unique epilepsy treatment in that a peripheral
intervention is used to treat a disease that is entirely related to pathological events occurring …