Background Idiopathic pulmonary fibrosis (IPF) is a chronic lung disorder of unknown origin,
which ultimately leads to death. Several growth factors such as IGFs (insulin-like-growth …

Idiopathic pulmonary fibrosis (IPF) is characterized by the rearrangement of extracellular
matrix and progressive increase in the amount of fibrotic tissue in the lung. IGF-I is a potent …

Idiopathic pulmonary fibrosis (IPF) is a fibrotic disease of unknown etiology that results in
significant morbidity and mortality. The pathogenesis of IPF is not completely understood …

For significant improvements to occur in the survival of patients with idiopathic pulmonary
fibrosis (IPF), it is necessary to develop novel and more precisely targeted therapies. The …

Idiopathic pulmonary fibrosis (IPF) is characterized by activated alveolar macrophages (AM),
alveolar epithelial cell proliferation and interstitial matrix, and immune complex deposition …

In a recent study of IFN-γ 1b in 330 patients with idiopathic pulmonary fibrosis (IPF),
progression-free survival was unchanged; however, a trend toward lower mortality was seen …

Idiopathic pulmonary fibrosis (IPF) is a deadly disease, largely unresponsive to treatment
with corticosteroids and immunosuppressives. The aim of this randomized, prospective …

Although most evident in the skin, the process of scarring, or fibrosis, occurs in all major
organs because of impaired epithelial self-renewal. No current therapy exists for Idiopathic …

Connective tissue growth factor is a recently described chemoattractant and fibroblast
mitogen which, because of sequence homology and weak binding to insulin-like growth …

Idiopathic pulmonary fibrosis (IPF) is a lung disease that is characterized by epithelial cell
damage and areas of denuded basement membrane resulting in inflammation, fibroblast …