COVID-19 has shaken the world and intensive care units (ICU) have been challenged by
numerous patients suffering from a previously unknown disease. Leptin is a polypeptide …

Excessive monocyte activation with the development of excessive or uncontrolled release of
proinflammatory cytokines often results in host tissue injury and even death in patients with …

Overweight and obesity are major risk factors for diabetes, cardiovascular disease, and lung
disease. These diseases are the most commonly reported health conditions that predispose …

Although many efforts have been made to understand the pathophysiological mechanisms
of COVID-19, critical gaps remain to be explored. This study aimed to investigate potential …

Obesity is one of the foremost risk factors in coronavirus infection resulting in severe illness
and mortality as the pandemic progresses. Obesity is a well-known predisposed chronic …

Introduction Obesity is commonly reported in COVID-19 patients and is associated with
poorer outcomes. It is suggested that leptin could be the missing link between obesity and …

Leptin is a pleiotropic adipocytokine involved in several physiologic functions, with a known
role in innate and adaptive immunity as well as in tissue homeostasis. Long-and short …

Obesity is a risk factor for SARS-CoV-2 infected patients to develop respiratory failure. Leptin
produced in visceral fat might play a role in the deterioration to mechanical ventilation. A …

In much of the developing world, severe malnutrition is the most prevalent cause of
immunodeficiency and affects up to 50% of the population in some impoverished …

Aim Obesity is a risk factor for COVID-19, but the underlying mechanisms are unclear. We
investigated the role of adiponectin (an anti-inflammatory adipokine), leptin (a pro …