Hesperidin as a neuroprotective agent: a review of animal and clinical evidence

M Hajialyani, M Hosein Farzaei, J Echeverría… - Molecules, 2019 - mdpi.com
Neuroprotection is the preservation of function and networks of neural tissues from damages
caused by various agents, as well as neurodegenerative diseases such as Parkinson's …

[HTML][HTML] The benefits of hesperidin in central nervous system disorders, based on the neuroprotective effect

X Li, W Huang, R Tan, C Xu, X Chen, S Li, Y Liu… - Biomedicine & …, 2023 - Elsevier
Disorders of central nervous system (CNS) disorders are considered serious health issues.
The most common CNS diseases include neurodegenerative diseases, mental disorders …

[HTML][HTML] Benefits of hesperidin in central nervous system disorders: a review

J Kim, MB Wie, M Ahn, A Tanaka, H Matsuda… - Anatomy & cell …, 2019 - ncbi.nlm.nih.gov
Citrus species contain significant amounts of flavonoids that possess antioxidant activities;
furthermore, dietary citrus is not associated with adverse effects or cytotoxicity in healthy …

Antioxidant and Anti-Inflammatory Effects of Citrus Flavonoid Hesperetin: Special Focus on Neurological Disorders

A Khan, M Ikram, JR Hahm, MO Kim - Antioxidants, 2020 - mdpi.com
Neurodegenerative disorders have emerged as a serious health issue in the current era.
The most common neurodegenerative disorders are Alzheimer's disease (AD), Parkinson's …

Hesperetin confers neuroprotection by regulating Nrf2/TLR4/NF-κB signaling in an Aβ mouse model

M Ikram, T Muhammad, SU Rehman, A Khan… - Molecular …, 2019 - Springer
Hesperetin is a bioactive flavonoid in the body, produced from hesperidin. No
comprehensive studies have shown its protective effects in neurodegenerative disorders …

Neuroprotective effects and therapeutic potential of the citrus flavonoid hesperetin in neurodegenerative diseases

JA Evans, P Mendonca, KFA Soliman - Nutrients, 2022 - mdpi.com
Neurodegenerative disorders affect more than fifty million Americans each year and
represent serious health threats as the population ages. Neuroinflammation and oxidative …

Antioxidant and neuroprotective effects of hesperidin and its aglycone hesperetin

J Cho - Archives of pharmacal research, 2006 - Springer
The present study evaluated antioxidant and neuroprotective activities of hesperidin, a
flavanone mainly isolated from citrus fruits, and its aglycone hesperetin using cell-free …

The pharmacological potential of hesperidin

A Ganeshpurkar, A Saluja - 2019 - nopr.niscpr.res.in
The modern scientific society has presently recognized flavonoids to be a unique class of
therapeutic molecules due to their varied therapeutic properties. Of these, hesperidin, found …

Hesperidin ameliorates cognitive dysfunction, oxidative stress and apoptosis against aluminium chloride induced rat model of Alzheimer's disease

A Justin Thenmozhi, TR William Raja… - Nutritional …, 2017 - Taylor & Francis
Background/aims: Deregulation of metal ion homeostasis has been assumed as one of the
key factors in the progression of neurodegenerative diseases. Aluminium (Al) has been …

Neuroprotective potentials of flavonoids: Experimental studies and mechanisms of action

P Bellavite - Antioxidants, 2023 - mdpi.com
Neurological and neurodegenerative diseases, particularly those related to aging, are on
the rise, but drug therapies are rarely curative. Functional disorders and the organic …