Midlife alcohol consumption and later life cognitive impairment: light drinking is not protective and APOE genotype does not change this relationship

EJ Chosy, S Edland, L Launer, LR White - PLoS One, 2022 - journals.plos.org
Introduction Much debate exists about the role of light to moderate alcohol intake and
subsequent cognitive function. The apolipoprotein E genotype may modify the relationship …

Midlife alcohol consumption and later risk of cognitive impairment: a twin follow-up study

JJ Virta, T Järvenpää, K Heikkilä… - Journal of …, 2010 - content.iospress.com
In this prospective follow-up study, we monitored the effects of midlife alcohol consumption
and drinking patterns on cognitive impairment risks in late life. 1,486 subjects recruited from …

The Relationship Between Midlife and Late Life Alcohol Consumption, APOE e4 and the Decline in Learning and Memory Among Older Adults

B Downer, F Zanjani, DW Fardo - Alcohol and Alcoholism, 2014 - academic.oup.com
Aims: The aim of the study was to determine whether the trajectory of learning and memory
is modified according to an interaction between midlife or late life alcohol consumption …

Interaction between alcohol consumption and apolipoprotein E (ApoE) genotype with cognition in middle-aged men

RE Slayday, DE Gustavson, JA Elman… - Journal of the …, 2021 - cambridge.org
Objective: Heavy alcohol consumption is associated with poorer cognitive function in older
adults. Although understudied in middle-aged adults, the relationship between alcohol and …

Apolipoprotein E4 genotype is not associated with short-term cognition deficits during alcohol withdrawal

J Wilhelm, N von Ahsen, H Frieling, T Hillemacher… - Alcohol, 2005 - Elsevier
Aim of this prospective study was to investigate a possible association between the
apolipoprotein E4 (ApoE4) genotype and clinically well-known cognition deficits during …

The effect of apolipoprotein E ε4 in the relationships of smoking and drinking to cognitive function

D Carmelli, GE Swan, T Reed, GD Schellenberg… - …, 1999 - karger.com
Objectives: To investigate the joint effect of the apolipoprotein E ε4 (APOE ε4), smoking and
drinking on cognitive performance in a population-based longitudinal study of elderly men …

Influence of apolipoprotein E genotype on the risk of cognitive deterioration in moderate drinkers and smokers

C Dufouil, C Tzourio, C Brayne, C Berr, P Amouyel… - …, 2000 - journals.lww.com
We investigated the risk of cognitive deterioration in relation to alcohol consumption and
smoking according to the apolipoprotein E (ApoE) polymorphism. The ApoE ε4 allele is an …

Effect of Apolipoprotein E ε4 on the association between health behaviors and cognitive function in late midlife

S Sabia, M Kivimaki, M Kumari, MJ Shipley… - Molecular …, 2010 - Springer
The extent to which the effect of risk factors on cognitive ageing is dependent on APOE ε4
remains unclear. The objective of this study is to examine whether APOE ε4 allele modifies …

Alcohol consumption in mild cognitive impairment and dementia: harmful or neuroprotective?

F Panza, V Frisardi, D Seripa… - … journal of geriatric …, 2012 - Wiley Online Library
Objective: In several longitudinal studies, light‐to‐moderate drinking of alcoholic beverages
has been proposed as being protective against the development of age‐related changes in …

Moderate alcohol use and apolipoprotein E-4 (ApoE-4): Independent effects on cognitive outcomes in later life

D Herring, D Paulson - Journal of Clinical and Experimental …, 2018 - Taylor & Francis
Objectives: Substantive past research suggests that moderate alcohol use confers beneficial
health outcomes. The study of moderate alcohol use and cognition has produced variable …