Porcine germline genome engineering
Germline editing, the process by which the genome of an individual is edited in such a way
that the change is heritable, has been applied to a wide variety of animals [DA Sorrell, AF …
that the change is heritable, has been applied to a wide variety of animals [DA Sorrell, AF …
Improvements in pig agriculture through gene editing
Genetic modification of animals via selective breeding is the basis for modern agriculture.
The current breeding paradigm however has limitations, chief among them is the …
The current breeding paradigm however has limitations, chief among them is the …
How genome editing changed the world of large animal research
K Fischer, A Schnieke - Frontiers in Genome Editing, 2023 - frontiersin.org
The first genetically modified large animals were developed in 1985 by microinjection to
increase the growth of agricultural livestock such as pigs. Since then, it has been a difficult …
increase the growth of agricultural livestock such as pigs. Since then, it has been a difficult …
Genome‐editing technologies to improve research, reproduction, and production in pigs
KD Wells, RS Prather - Molecular Reproduction and …, 2017 - Wiley Online Library
The ability to directly manipulate the pig genome through genetic engineering has been
available to the research community for over three decades. This technology has …
available to the research community for over three decades. This technology has …
Perspectives in Genome-Editing Techniques for Livestock
J Popova, V Bets, E Kozhevnikova - Animals, 2023 - mdpi.com
Simple Summary Genetically modified farm animals have been actively used in a number of
applications from testing gene functions to increasing production and economic value of …
applications from testing gene functions to increasing production and economic value of …
Current progress of genome editing in livestock
Historically, genetic engineering in livestock proved to be challenging. Without stable
embryonic stem cell lines to utilize, somatic cell nuclear transfer (SCNT) had to be employed …
embryonic stem cell lines to utilize, somatic cell nuclear transfer (SCNT) had to be employed …
Genome editing of pigs for agriculture and biomedicine
H Yang, Z Wu - Frontiers in Genetics, 2018 - frontiersin.org
Pigs serve as an important agricultural resource and animal model in biomedical studies.
Efficient and precise modification of pig genome by using recently developed gene editing …
Efficient and precise modification of pig genome by using recently developed gene editing …
Genome editing approaches to augment livestock breeding programs
TF Bishop, AL Van Eenennaam - Journal of Experimental …, 2020 - journals.biologists.com
The prospect of genome editing offers a number of promising opportunities for livestock
breeders. Firstly, these tools can be used in functional genomics to elucidate gene function …
breeders. Firstly, these tools can be used in functional genomics to elucidate gene function …
Current status of the application of gene editing in pigs
F Tanihara, M Hirata, T Otoi - Journal of Reproduction and …, 2021 - jstage.jst.go.jp
Genetically modified animals, especially rodents, are widely used in biomedical research.
However, non-rodent models are required for efficient translational medicine and preclinical …
However, non-rodent models are required for efficient translational medicine and preclinical …
Genome editing revolutionize the creation of genetically modified pigs for modeling human diseases
J Yao, J Huang, J Zhao - Human genetics, 2016 - Springer
Pigs have anatomical, physiological and genomic characteristics that make them highly
suitable for modeling human diseases. Genetically modified (GM) pig models of human …
suitable for modeling human diseases. Genetically modified (GM) pig models of human …