Ancient DNA sequencing has recently provided high-coverage archaic human genomes.
However, the evolution of epigenetic regulation along the human lineage remains largely …

The recent discovery that DNA methylation survives in fossil material provides an
opportunity for novel molecular approaches in palaeogenomics. Here, we apply to ancient …

How do epigenetic modifications change across species and how do these modifications
affect evolution? These are fundamental questions at the forefront of our evolutionary …

Epigenetic information is available from contemporary organisms, but is difficult to track back
in evolutionary time. Here, we show that genome-wide epigenetic information can be …

Epigenetic changes to gene expression can result in heritable phenotypic characteristics
that are not encoded in the DNA itself, but rather by biochemical modifications to the DNA or …

Despite the increasing knowledge about DNA methylation, the understanding of human
epigenome evolution is in its infancy. Using whole genome bisulfite sequencing we …

Denisovans are an extinct group of humans whose morphology remains unknown. Here, we
present a method for reconstructing skeletal morphology using DNA methylation patterns …

DNA methylation is a pervasive epigenetic DNA modification that strongly affects chromatin
regulation and gene expression. To date, it remains largely unknown how patterns of DNA …

Background Dynamic changes to the epigenome play a critical role in establishing and
maintaining cellular phenotype during differentiation, but little is known about the normal …

Introduction Several lines of evidence point to a key role for dynamic epigenetic changes
during brain development, maturation, and learning. DNA methylation (mC) is a stable …