Critical review on the analytical methods for the estimation of clofazimine in bulk, biological fluids and pharmaceutical formulations
TS Patil, AS Deshpande… - Critical Reviews in …, 2018 - Taylor & Francis
Clofazimine (CFZ), a riminophenazine derivative and a crucial drug in the treatment of
lepromatous leprosy, has been reintroduced clinically to treat multidrug-resistant …
lepromatous leprosy, has been reintroduced clinically to treat multidrug-resistant …
Quantitative analysis of clofazimine (Lamprene®), an antileprosy agent, in human dried blood spots using liquid chromatography–tandem mass spectrometry
W Li, J Doherty, Y Fu, J Flarakos - Biomedical Chromatography, 2018 - Wiley Online Library
Abstract An LC–MS/MS method was developed and validated for bioanalysis of clofazimine
in human dried blood spot (DBS) samples in support of a clinical study on multidrug …
in human dried blood spot (DBS) samples in support of a clinical study on multidrug …
Quantification of Clofarabine and its impurity substances by RP-HPLC method in parenteral formulation
A simple, accurate and precise stability-indicating RP-HPLC method was developed for
estimation of clofarabine in parenteral formulation. Some known impurities like, alpha …
estimation of clofarabine in parenteral formulation. Some known impurities like, alpha …
[HTML][HTML] A rapid and sensitive high performance liquid chromatographic analysis of clofazimine in plasma
TR Krishnan, I Abraham - International journal of leprosy and other …, 1992 - ijl.ilsl.br
The high performance liquid chromatographic (HPLC) method of Gidoh, et al. has been
modified substantially to provide a simple, rapid, and relatively inexpensive procedure for …
modified substantially to provide a simple, rapid, and relatively inexpensive procedure for …
Development of an innovative quality by design (QbD) based stability-indicating HPLC method and its validation for clofazimine from its bulk and pharmaceutical …
TS Patil, AS Deshpande - Chromatographia, 2019 - Springer
The present research work discusses the systematic Quality by Design (QbD) enabled
development of a simple, rapid, economical, and stability-indicating high-performance liquid …
development of a simple, rapid, economical, and stability-indicating high-performance liquid …
[PDF][PDF] Quantification of newer anti-cancer drug clofarabine in their bulk and pharmaceutical dosage form
BD Patel, UK Chhalotiya, DB Patel - J Chromatogr Sep Tech, 2016 - academia.edu
Quantitative determination of Clofarabine in their Pharmaceutical Dosage form was carried
out by Liquid chromatographic method. The aim of the present work was to develop a RP …
out by Liquid chromatographic method. The aim of the present work was to develop a RP …
Pharmacokinetics and relative bioavailability of clofazimine in relation to food, orange juice and antacid
Background: Clofazimine is potentially useful for the treatment of disease due to multidrug
resistant Mycobacterium tuberculosis, as well as leprosy and certain chronic skin diseases …
resistant Mycobacterium tuberculosis, as well as leprosy and certain chronic skin diseases …
Characterization of Clofazimine Metabolism in Human Liver Microsomal Incubation In Vitro
ABSTRACT Clofazimine [N, 5-bis (4-chlorophenyl)-3-[(propane-2-yl) rimino]-3, 5-
dihydrophenazin-2-amine] is an antimycobacterial agent used as a second-line …
dihydrophenazin-2-amine] is an antimycobacterial agent used as a second-line …
Clofazimine: an old drug for never-ending diseases
N Riccardi, A Giacomelli, D Canetti, A Comelli… - Future …, 2020 - Taylor & Francis
Clofazimine (CFZ), an old hydrophobic riminophenazine, has a wide range of
antimycobacterial activity ranging from leprosy to nontuberculous mycobacterial diseases …
antimycobacterial activity ranging from leprosy to nontuberculous mycobacterial diseases …
[引用][C] Determination of clofazimine in human plasma by thin-layer chromatography
Z Lanyi, JP Dubois - Journal of Chromatography B: Biomedical Sciences …, 1982 - Elsevier
To date, Barry et al.[l] and Dill et al.[2] have reported, respectively, a spectrophotometric and
a fluorometric method of assay for clofazimine in biological fluids and tissue homogenates …
a fluorometric method of assay for clofazimine in biological fluids and tissue homogenates …