Long non-coding RNAs as a determinant of cancer drug resistance: Towards the overcoming of chemoresistance via modulation of lncRNAs

W Jiang, J Xia, S Xie, R Zou, S Pan, Z Wang… - Drug Resistance …, 2020 - Elsevier
Chemoresistance including intrinsic and acquired anticancer drug resistance continues to
be a primary hindrance towards curative cancer treatment. Therefore, deciphering the …

Long non-coding RNA: a recently accentuated molecule in chemoresistance in cancer

Y Peng, D Tang, M Zhao, H Kajiyama… - Cancer and Metastasis …, 2020 - Springer
Chemotherapy is one of the important and effective options for cancer treatment in the past
decades. Although the response rate of initial chemotherapy is considerably high in certain …

Long non-coding RNAs (lncRNAs) signaling in cancer chemoresistance: from prediction to druggability

GC Eptaminitaki, D Stellas, B Bonavida… - Drug Resistance Updates, 2022 - Elsevier
The acquisition of cancer cell resistance to conventional chemotherapeutics is considered
the major driver of treatment failure and disease recurrence in most solid and hematological …

[HTML][HTML] Long non-coding RNAs in anti-cancer drug resistance

Q Chen, C Wei, Z Wang, M Sun - Oncotarget, 2017 - ncbi.nlm.nih.gov
Chemotherapy is one of the basic treatments for cancers; however, drug resistance is mainly
responsible for the failure of clinical treatment. The mechanism of drug resistance is …

Long non-coding RNAs in cancer drug resistance development

M Majidinia, B Yousefi - DNA repair, 2016 - Elsevier
The presence or emergence of chemoresistance in tumor cells is a major burden in cancer
therapy. While drug resistance is a multifactorial phenomenon arising from altered …

Non-coding RNA in cancer drug resistance: Underlying mechanisms and clinical applications

X Zhou, X Ao, Z Jia, Y Li, S Kuang, C Du… - Frontiers in …, 2022 - frontiersin.org
Cancer is one of the most frequently diagnosed malignant diseases worldwide, posing a
serious, long-term threat to patients' health and life. Systemic chemotherapy remains the first …

LncRNA as a multifunctional regulator in cancer multi-drug resistance

J He, S Zhu, X Liang, Q Zhang, X Luo, C Liu… - Molecular Biology …, 2021 - Springer
Background Malignant tumors have become the most dangerous disease in recent years.
Chemotherapy is the most effective treatment for this disease; however, the problem of drug …

Long non-coding RNAs regulate drug resistance in cancer

K Liu, L Gao, X Ma, JJ Huang, J Chen, L Zeng… - Molecular cancer, 2020 - Springer
Chemoresistance, whether intrinsic or acquired, is a major obstacle in the treatment of
cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various …

Role of long non-coding RNA in tumor drug resistance

H Deng, J Zhang, JJ Shi, ZD Guo, CR He, L Ding… - Tumor Biology, 2016 - Springer
Chemotherapy has been extensively used in tumor treatment, including either systemic or
local treatment. Miserably, in many kinds of cancers, chemotherapy is gradually insensitive …

Long non-coding RNA mediated drug resistance in breast cancer

D Singh, YG Assaraf, RN Gacche - Drug Resistance Updates, 2022 - Elsevier
Breast cancer is one of the most prevalent cancers in women and a leading cause of
mortality. As per the GLOBCAN report of 2021, breast cancer has surpassed lung cancer …