Managing competing goals—a key role for the frontopolar cortex

FA Mansouri, E Koechlin, MGP Rosa… - Nature Reviews …, 2017 - nature.com
Humans are set apart from other animals by many elements of advanced cognition and
behaviour, including language, judgement and reasoning. What is special about the human …

Anterior prefrontal function and the limits of human decision-making

E Koechlin, A Hyafil - Science, 2007 - science.org
The frontopolar cortex (FPC), the most anterior part of the frontal lobes, forms the apex of the
executive system underlying decision-making. Here, we review empirical evidence showing …

Frontal pole cortex: encoding ends at the end of the endbrain

S Tsujimoto, A Genovesio, SP Wise - Trends in cognitive sciences, 2011 - cell.com
Considerable neuroimaging research in humans indicates that the frontal pole cortex (FPC),
also known as Brodmann area 10, contributes to many aspects of cognition. Despite these …

The whole prefrontal cortex is premotor cortex

JM Fine, BY Hayden - Philosophical Transactions of the …, 2022 - royalsocietypublishing.org
We propose that the entirety of the prefrontal cortex (PFC) can be seen as fundamentally
premotor in nature. By this, we mean that the PFC consists of an action abstraction hierarchy …

The role of the anterior prefrontal cortex in human cognition

E Koechlin, G Basso, P Pietrini, S Panzer, J Grafman - Nature, 1999 - nature.com
Complex problem-solving and planning involve the most anterior part of the frontal lobes
including the fronto-polar prefrontal cortex (FPPC),,,,,, which is especially well developed in …

Essential functions of primate frontopolar cortex in cognition

EA Boschin, C Piekema… - Proceedings of the …, 2015 - National Acad Sciences
Brodmann's area 10 is one of the largest cytoarchitecturally defined regions in the human
cerebral cortex, occupying the most anterior part of the prefrontal cortex [frontopolar cortex …

Prefrontal cortex and cognitive control: motivating functional hierarchies

T Egner - Nature neuroscience, 2009 - nature.com
Prefrontal cortex and cognitive control: motivating functional hierarchies | Nature Neuroscience
Skip to main content Thank you for visiting nature.com. You are using a browser version with …

[HTML][HTML] Damage to the fronto-polar cortex is associated with impaired multitasking

JC Dreher, E Koechlin, M Tierney, J Grafman - PLoS One, 2008 - journals.plos.org
Background A major question in understanding the functional organization of the brain is to
delineate the functional divisions of the prefrontal cortex. Of particular importance to the …

The role of the medial prefrontal cortex in achieving goals

K Matsumoto, K Tanaka - Current opinion in neurobiology, 2004 - Elsevier
Achieving goals in changing environments requires the course of action to be selected on
the basis of goal expectation and memory of action–outcome contingency. It is often also …

The prefontral cortex and cognitive control

EK Miller - Nature reviews neuroscience, 2000 - nature.com
One of the enduring mysteries of brain function concerns the process of cognitive control.
How does complex and seemingly wilful behaviour emerge from interactions between …