Background Optimal protocols for efficient and reproducible protein extraction from formalin-
fixed paraffin-embedded (FFPE) tissues are not yet standardised and new techniques are …

Tissue‐based proteomic approaches (tissue proteomics) are essential for discovering and
evaluating biomarkers for personalized medicine. In any proteomics study, the most critical …

Proteomic analysis of clinical samples has been traditionally performed using fresh or frozen
tissues. However, millions of embedded samples are stored worldwide in pathology …

We determined the best extraction buffer for proteomic investigation using formalin-fixation
and paraffin-embedded (FFPE) specimens. A Zwittergent 3–16 based buffer, sodium …

Formalin-fixed paraffin-embedded (FFPE) tissue specimens represent a potential valuable
source of samples for clinical research. Since these specimens are banked in hospital …

A sample preparation procedure has been developed to prepare Formalin-Fixed Paraffin-
Embedded (FFPE) tissues for proteomic profiling. Protocols have been established for …

In most hospitals worldwide formalin-fixation and paraffin-embedding (FFPE) is the standard
tissue fixation and storage method. The analysis and extraction of full-length and …

Objectives Formalin-fixed paraffin-embedded (FFPE) tissue is the standard material for
diagnostic pathology but poses relevant hurdles to accurate protein extraction due to cross …

Most tissue biopsies from patients in hospital environments are formalin-fixed and paraffin-
embedded (FFPE) for long-term storage. This fixation process produces a modification in the …

Purpose FFPE (formalin fixed, paraffin embedded) tissue cohorts represent an enduring
archive of clinical specimens. Proteomic analysis of FFPE tissues is gaining interest for the …