Apoptosis is the programmed cell death which maintains the healthy survival/death balance
in metazoan cells. Defect in apoptosis can cause cancer or autoimmunity, while enhanced …

Various physiological processes involve appropriate tissue developmental process and
homeostasis-the pathogenesis of several diseases connected with deregulatory apoptosis …

Programmed cell death (PCD) or apoptosis is a mechanism which is crucial for all
multicellular organisms to control cell proliferation and maintain tissue homeostasis as well …

Apoptosis is a tightly regulated cell suicide program that plays an essential role in the
development and maintenance of tissue homeostasis by eliminating unnecessary or harmful …

Recent knowledge on apoptosis has made it possible to devise novel approaches, which
exploit this process to treat cancer. In this review, we discuss in detail approaches to induce …

Introduction 3. The biochemistry of apoptosis 3.1 The executioner and its substrates 3.2
Channeling our attention on the Bcl-2 family 3.3 The Fas way to apoptosis 3.4 The PI3-K/Akt …

Our somatic cells are born by mitosis and almost all will die by apoptosis, a physiological
process of cellular suicide. Cancers can occur when this balance is disturbed, either by an …

For over three decades, a mainstay and goal of clinical oncology has been the development
of therapies promoting the effective elimination of cancer cells by apoptosis. This …

Apoptosis is an evolutionarily conserved sequential process of cell death to maintain a
homeostatic balance between cell formation and cell death. It is a vital process for normal …

Apoptosis is an ordered and orchestrated cellular process that occurs in physiological and
pathological conditions. It is also one of the most studied topics among cell biologists. An …