A recent large genome-wide association study has identified EGFR (encoding the epidermal
growth factor EGFR) as a new genetic risk factor for late-onset AD. SHIP2, encoded by …

Abstract Introduction Mutations in INPP5D, which encodes for the SH2‐domain‐containing
inositol phosphatase SHIP‐1, have recently been linked to an increased risk of developing …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
cognitive decline, robust microgliosis, neuroinflammation, and neuronal loss. Genome-wide …

Alzheimer's disease (AD) is the most common form of dementia, accounting for
approximately 38.5 million cases of all-cause dementia. Over 60% of these individuals live …

INTRODUCTION The risk of developing Alzheimer's disease is associated with genes
involved in microglial function. Inositol polyphosphate‐5‐phosphatase (INPP5D), which …

Background Recent evidence including GWAS and differential gene expression comparing
normal to affected Alzheimer's brain tissue have identified risk and protective variants in …

Alzheimer's disease (AD) pathology is associated with two proteins, the microtubule-binding
protein tau and the β-amyloid-precursor protein (APP). When tau becomes …

Alzheimer's disease (AD), the most common form of dementia, is characterized by the
presence of neurofibrillary tangles composed of tau and senile plaques of amyloid-beta …

Background Peptidyl-prolyl isomerase, NIMA-interacting 1 (PIN1) plays a significant role in
the brain and is implicated in numerous cellular processes related to Alzheimer's disease …

In our study, we analyzed the coding and promoter regions of the PIN1 gene in a group of
111 Alzheimer's disease (AD) patients looking for a possible genotype–phenotype …