Detrimental inflammatory responses after solid organ transplantation are initiated when
immune cells sense pathogen-associated molecular patterns (PAMPs) and certain damage …

Endogenous danger signals, or damage-associated molecular patterns (DAMPs), are
generated in response to cell stress and activate innate immunity to provide a pivotal …

The activation of host's innate and adaptive immune systems can lead to acute and chronic
graft rejection, which seriously impacts graft survival. Thus, it is particularly significant to …

Graft-versus-host response after allogeneic hematopoietic stem cell transplantation (allo-
HCT) represents one of the most intense inflammatory responses observed in humans. Host …

Graft inflammation impairs the induction of solid organ transplant tolerance and enhances
acute and chronic rejection. Elucidating the mechanisms by which inflammation is induced …

Sterile inflammation is the immune response to damage-associated molecular patterns
(DAMPs) released during cell death in the absence of foreign pathogens. In the setting of …

The life-saving benefits of organ transplantation can be thwarted by allograft dysfunction due
to both infectious and sterile inflammation post-surgery. Sterile inflammation can occur after …

Part 2 of the review focuses on the potential of oxidative injury–induced damage-associated
molecular patterns (DAMPs) to generate immunostimulatory dendritic cells (DCs) translating …

Significant strides have been made in our understanding of the immune system and its role
in cardiac transplant rejection. Despite the growing knowledge of immune responses, the …

The core of this three-volume book deals with damage-associated molecular patterns
abbreviated “DAMPs”, which are unique molecules that save life and fight for survival of all …