Light-emitting diodes as a light source for intraoperative photodynamic therapy

MH Schmidt, DM Bajic, KW Reichert, TS Martin… - …, 1996 - journals.lww.com
Abstract THE DEVELOPMENT OF more cost-effective light sources for photodynamic
therapy of brain tumors would be of benefit for both research and clinical applications. In this …

The role of photodynamic therapy in posterior fossa brain tumors: A preclinical study in a canine glioma model

HT Whelan, MH Schmidt, AD Segura… - Journal of …, 1993 - thejns.org
✓ Photodynamic therapy was studied in dogs with and without posterior fossa
glioblastomas. This mode of therapy consisted of intravenous administration of Photofrin-II at …

Photodynamic therapy of brain tumors—a work in progress

PJ Muller, BC Wilson - Lasers in Surgery and Medicine: The …, 2006 - Wiley Online Library
Background and Objectives PDT has been used in the treatment of malignant brain tumors.
This communication updates our series of unselected malignant gliomas treated with …

Evaluation of photodynamic therapy near functional brain tissue in patients with recurrent brain tumors

MH Schmidt, GA Meyer, KW Reichert, J Cheng… - Journal of neuro …, 2004 - Springer
Introduction: Photodynamic therapy (PDT) involves the selective retention of a
photosensitizer that upon activation with light mediates tumor cell destruction via the …

Photodynamic therapy using Photofrin in combination with buthionine sulfoximine (BSO) to treat 9L gliosarcoma in rat brain

F Jiang, L Lilge, M Belcuig, G Singh… - Lasers in Surgery …, 1998 - Wiley Online Library
Abstract Background and Objective: The reactive oxygen mechanisms associated with cell
damage after photodynamic therapy (PDT) may be exploited to enhance tumor destruction …

Photofrin photodynamic therapy for malignant brain tumors

PJ Muller, BC Wilson, LD Lilge… - Optical Methods for …, 2001 - spiedigitallibrary.org
In a phase II trial we treated more than 100 patients with malignant brain tumors with 2-
mg/kg Photofrin iv. and intraoperative cavitary PDT. We concluded that PDT was safe in …

A multispectral fluorescence imaging system: Design and initial clinical tests in intra‐operative Photofrin‐photodynamic therapy of brain tumors

VXD Yang, PJ Muller, P Herman… - Lasers in surgery and …, 2003 - Wiley Online Library
Abstract Background and Objectives Intra‐operative identification of tumor by fluorescence
may improve surgical resection or photodynamic therapy (PDT). A novel instrument was …

A novel device for intraoperative photodynamic therapy dedicated to glioblastoma treatment

C Dupont, S Mordon, P Deleporte, N Reyns… - Future …, 2017 - Future Medicine
Aim: Photodynamic therapy (PDT) appears to be a valuable new treatment modality for
cancer therapy. Studies have reported successful application of PDT for glioblastoma. Here …

Photodynamic therapy of U87 human glioma in nude rat using liposome‐delivered photofrin

F Jiang, L Lilge, J Grenier, Y Li… - Lasers in Surgery …, 1998 - Wiley Online Library
Abstract Background and Objective Liposomes as photosensitizer carriers may enhance the
photodynamic effect on tumors. Study Design/Materials and Methods: To test this …

Photodynamic therapy with Photofrin reduces invasiveness of malignant human glioma cells

F Jiang, M Chopp, M Katakowski, KK Cho… - Lasers in medical …, 2002 - Springer
In this study we investigated the influence of Photofrin-based photodynamic therapy (PDT)
on the migration of two human glioma cell lines in vitro. U87 and U25ln tumour cells were …