Correlation between virulence of Candida albicans mutants in mice and Galleria mellonella larvae

M Brennan, DY Thomas, M Whiteway… - FEMS Immunology & …, 2002 - academic.oup.com
Candida albicans is a dimorphic human pathogen in which the yeast to hyphal switch may
be an important factor in virulence in mammals. This pathogen has recently been shown to …

[HTML][HTML] Galleria mellonella as a model host to study virulence of Candida

ID Jacobsen - Virulence, 2014 - Taylor & Francis
238 Virulence Volume 5 issue 2 been associated with virulence in C. albicans and C.
parapsilosis. 28, 29 Both Gago et al. and Németh et al. analyzed enzymatic activity in the …

Development of an insect model for the in vivo pathogenicity testing of yeasts

G Cotter, S Doyle, K Kavanagh - FEMS Immunology & Medical …, 2000 - academic.oup.com
Conventional in vivo assays to determine the relative pathogenicity of yeast isolates rely
upon the use of a range of mammalian species. The purpose of the work presented here …

The non-mammalian host Galleria mellonella can be used to study the virulence of the fungal pathogen Candida tropicalis and the efficacy of antifungal drugs during …

AC Mesa-Arango, A Forastiero… - Medical …, 2013 - academic.oup.com
Although Candida tropicalis is a frequent cause of invasive fungal diseases, its interaction
with the host remains poorly studied. Galleria mellonella is a Lepidoptera model which offers …

Adaptation of Candida albicans to the host environment: the role of morphogenesis in virulence and survival in mammalian hosts

L Romani, F Bistoni, P Puccetti - Current opinion in microbiology, 2003 - Elsevier
Although morphological flexibility could be a key contributor to fungal virulence, no
molecular data has unambiguously established fungal morphogenesis as a virulence factor …

[PDF][PDF] Candida albicans: genetics, dimorphism and pathogenicity

G Molero, R Diez-Orejas, F Navarro-Garcia… - International …, 1998 - researchgate.net
Candida albicans is a dimorphic fungus that causes severe opportunistic infections in
humans. Recent advances in molecular biology techniques applied to this organism …

Candida albicans Hyphal Formation and Virulence Assessed Using a Caenorhabditis elegans Infection Model

R Pukkila-Worley, AY Peleg, E Tampakakis… - Eukaryotic …, 2009 - Am Soc Microbiol
Candida albicans colonizes the human gastrointestinal tract and can cause life-threatening
systemic infection in susceptible hosts. We study here C. albicans virulence determinants …

Candida albicans Killing by RAW 264.7 Mouse Macrophage Cells: Effects of Candida Genotype, Infection Ratios, and Gamma Interferon Treatment

A Marcil, D Harcus, DY Thomas… - Infection and …, 2002 - Am Soc Microbiol
Phagocytic cells such as neutrophils and macrophages are potential components of the
immune defense that protects mammals against Candida albicans infection. We have tested …

Candida albicans, a major human fungal pathogen

J Kim, P Sudbery - The journal of microbiology, 2011 - Springer
Candida albicans is the most common human fungal pathogen (Beck-Sague and Jarvis,
1993). It is normally a harmless commensal organism. However, it is a opportunistic …

Regulation of phenotypic transitions in the fungal pathogen Candida albicans

G Huang - Virulence, 2012 - Taylor & Francis
The human commensal fungus Candida albicans can cause not only superficial infections,
but also life-threatening disease in immunocompromised individuals. C. albicans can grow …