Among the devices employed for aerosol generation (metered-dose inhalers, nebulizers,
and dry powder inhalers) only metered-dose inhalers and nebulizers are routinely employed …

Pressurized metered-dose inhalers (pMDIs) and nebulizers are routinely employed for
aerosol delivery in mechanically ventilated patients. A significant proportion of the aerosol …

During the past decade the unprecedented improvements in technology for delivery of
inhaled drugs were matched by an equally impressive growth in clinical applications …

The delivery of aerosols to mechanically ventilated patients presents unique challenges and
differs from inhaled drug delivery in spontaneously breathing patients in several respects …

Inhaled therapy is commonly employed in mechanically ventilated patients with chronic
obstructive pulmonary disease or asthma. The efficacy of inhaled drugs is comparable to …

Inhaled therapy has been routinely employed for over half a century in ambulatory patients
with respiratory disorders. In contrast, many barriers were previously thought to preclude …

Objective To provide an overview of aerosol drug delivery during mechanical ventilation in
the pediatric and adult populations. Data Sources Published articles and abstracts identified …

Aerosol delivery via a mechanical ventilator remains unregulated with no standards for drug
delivery to intubated patients. Bench models predicting drug delivery have not been …

Incremental gains in understanding the influence of various factors on aerosol delivery in
concert with technological advancements over the past 2 decades have fueled an ever …

Pressurized metered-dose inhalers (pMDIs) and nebulizers are employed routinely for
aerosol delivery to ventilator-supported patients, but the ventilator circuit and artificial airway …