Inter-species geographic signatures for tracing horizontal gene transfer and long-term persistence of carbapenem resistance
Abstract Background Carbapenem-resistant Enterobacterales (CRE) are an urgent global
health threat. Inferring the dynamics of local CRE dissemination is currently limited by our …
health threat. Inferring the dynamics of local CRE dissemination is currently limited by our …
Genomically informed surveillance for carbapenem-resistant Enterobacteriaceae in a health care system
Carbapenem-resistant Enterobacteriaceae (CRE) are an urgent public health concern.
Rapid identification of the resistance genes, their mobilization capacity, and strains carrying …
Rapid identification of the resistance genes, their mobilization capacity, and strains carrying …
Whole-genome sequencing to identify drivers of carbapenem-resistant Klebsiella pneumoniae transmission within and between regional long-term acute-care …
Carbapenem-resistant Klebsiella pneumoniae (CRKP) is an antibiotic resistance threat of
the highest priority. Given the limited treatment options for this multidrug-resistant organism …
the highest priority. Given the limited treatment options for this multidrug-resistant organism …
The role of plasmids in carbapenem resistant E. coli in Alameda County, California
Background Antimicrobial resistant infections continue to be a leading global public health
crisis. Mobile genetic elements, such as plasmids, have been shown to play a major role in …
crisis. Mobile genetic elements, such as plasmids, have been shown to play a major role in …
Single-molecule sequencing to track plasmid diversity of hospital-associated carbapenemase-producing Enterobacteriaceae
S Conlan, PJ Thomas, C Deming, M Park… - Science translational …, 2014 - science.org
Public health officials have raised concerns that plasmid transfer between
Enterobacteriaceae species may spread resistance to carbapenems, an antibiotic class of …
Enterobacteriaceae species may spread resistance to carbapenems, an antibiotic class of …
Accessory genomes drive independent spread of carbapenem-resistant Klebsiella pneumoniae clonal groups 258 and 307 in Houston, TX
WC Shropshire, AQ Dinh, M Earley, L Komarow… - MBio, 2022 - Am Soc Microbiol
Carbapenem-resistant Klebsiella pneumoniae (CR Kp) is an urgent public health threat.
Worldwide dissemination of CR Kp has been largely attributed to clonal group (CG) 258 …
Worldwide dissemination of CR Kp has been largely attributed to clonal group (CG) 258 …
[HTML][HTML] Whole-genome sequence analysis of carbapenem-resistant Enterobacteriaceae recovered from hospitalized patients
M El Khoury, T Salloum, I Al Kodsi, T Jisr… - Journal of Global …, 2023 - Elsevier
Objectives Carbapenems are among the few effective antibiotics against multidrug-resistant
Enterobacteriaceae. This study aimed at characterizing the plasmid content and resistome of …
Enterobacteriaceae. This study aimed at characterizing the plasmid content and resistome of …
Molecular dissection of an outbreak of carbapenem-resistant Enterobacteriaceae reveals intergenus KPC carbapenemase transmission through a promiscuous …
AJ Mathers, HL Cox, B Kitchel, H Bonatti… - MBio, 2011 - Am Soc Microbiol
Carbapenem-resistant Enterobacteriaceae (CRE) have emerged as major causes of health
care-associated infections worldwide. This diverse collection of organisms with various …
care-associated infections worldwide. This diverse collection of organisms with various …
National genomic surveillance integrating standardized quantitative susceptibility testing clarifies antimicrobial resistance in Enterobacterales
S Kayama, K Yahara, Y Sugawara, S Kawakami… - Nature …, 2023 - nature.com
Antimicrobial resistance is a global health concern; Enterobacterales resistant to third-
generation cephalosporins (3GCs) and carbapenems are of the highest priority. Here, we …
generation cephalosporins (3GCs) and carbapenems are of the highest priority. Here, we …
Mechanisms of evolution in high-consequence drug resistance plasmids
The dissemination of resistance among bacteria has been facilitated by the fact that
resistance genes are usually located on a diverse and evolving set of transmissible …
resistance genes are usually located on a diverse and evolving set of transmissible …