[HTML][HTML] The metabolic basis for nervous system dysfunction in alzheimer's disease, parkinson's disease, and huntington's disease
K Maiese - Current neurovascular research, 2023 - ncbi.nlm.nih.gov
Disorders of metabolism affect multiple systems throughout the body, but may have the
greatest impact on both central and peripheral nervous systems. Current available …
greatest impact on both central and peripheral nervous systems. Current available …
Metabolic dysfunction in Alzheimer's disease and related neurodegenerative disorders
Alzheimer's disease and other related neurodegenerative diseases are highly debilitating
disorders that affect millions of people worldwide. Efforts towards developing effective …
disorders that affect millions of people worldwide. Efforts towards developing effective …
Neurodegenerative diseases–is metabolic deficiency the root cause?
VR Muddapu, SAP Dharshini… - Frontiers in …, 2020 - frontiersin.org
Neurodegenerative diseases, including Alzheimer, Parkinson, Huntington, and amyotrophic
lateral sclerosis, are a prominent class of neurological diseases currently without a cure …
lateral sclerosis, are a prominent class of neurological diseases currently without a cure …
Metabolic features of brain function with relevance to clinical features of Alzheimer and Parkinson diseases
DA Butterfield, M Favia, I Spera, A Campanella… - Molecules, 2022 - mdpi.com
Brain metabolism is comprised in Alzheimer's disease (AD) and Parkinson's disease (PD).
Since the brain primarily relies on metabolism of glucose, ketone bodies, and amino acids …
Since the brain primarily relies on metabolism of glucose, ketone bodies, and amino acids …
Potential mechanisms to modify impaired glucose metabolism in neurodegenerative disorders
TS McDonald, T Lerskiatiphanich… - Journal of Cerebral …, 2023 - journals.sagepub.com
Neurodegeneration refers to the selective and progressive loss-of-function and atrophy of
neurons, and is present in disorders such as Alzheimer's, Huntington's, and Parkinson's …
neurons, and is present in disorders such as Alzheimer's, Huntington's, and Parkinson's …
Dysregulation of metabolic flexibility: The impact of mTOR on autophagy in neurodegenerative disease
K Maiese - International review of neurobiology, 2020 - Elsevier
Non-communicable diseases (NCDs) that involve neurodegenerative disorders and
metabolic disease impact over 400 million individuals globally. Interestingly, metabolic …
metabolic disease impact over 400 million individuals globally. Interestingly, metabolic …
Metabolic dysfunction in Alzheimer's disease: from basic neurobiology to clinical approaches
Clinical trials have extensively failed to find effective treatments for Alzheimer's disease (AD)
so far. Even after decades of AD research, there are still limited options for treating …
so far. Even after decades of AD research, there are still limited options for treating …
Altered substrate metabolism in neurodegenerative disease: new insights from metabolic imaging
NRW Cleland, SI Al-Juboori, E Dobrinskikh… - Journal of …, 2021 - Springer
Neurodegenerative diseases (NDs), such as Alzheimer's disease (AD), Parkinson's disease
(PD) and multiple sclerosis (MS), are relatively common and devastating neurological …
(PD) and multiple sclerosis (MS), are relatively common and devastating neurological …
Cellular metabolism: A fundamental component of degeneration in the nervous system
K Maiese - Biomolecules, 2023 - mdpi.com
It is estimated that, at minimum, 500 million individuals suffer from cellular metabolic
dysfunction, such as diabetes mellitus (DM), throughout the world. Even more concerning is …
dysfunction, such as diabetes mellitus (DM), throughout the world. Even more concerning is …
The triangle of death in Alzheimer's disease brain: the aberrant cross-talk among energy metabolism, mammalian target of rapamycin signaling, and protein …
Significance: Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder and
represents one of the most disabling conditions. AD shares many features in common with …
represents one of the most disabling conditions. AD shares many features in common with …
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