[HTML][HTML] Epstein-Barr virus, interleukin-10 and multiple sclerosis: A ménage à trois

G Schönrich, MO Abdelaziz, MJ Raftery - Frontiers in Immunology, 2022 - frontiersin.org
Multiple Sclerosis (MS) is an autoimmune disease that is characterized by inflammation and
demyelination of nerve cells. There is strong evidence that Epstein-Barr virus (EBV), a …

[HTML][HTML] Altered immune response to the epstein–barr virus as a prerequisite for multiple sclerosis

F Läderach, C Münz - Cells, 2022 - mdpi.com
Strong epidemiologic evidence links Epstein–Barr virus (EBV) infection and its altered
immune control to multiple sclerosis (MS) development. Clinical MS onset occurs years after …

MINI-review of Epstein-Barr virus involvement in multiple sclerosis etiology and pathogenesis

F Aloisi, AH Cross - Journal of Neuroimmunology, 2022 - Elsevier
Epstein-Barr virus (EBV) is the infectious agent that shows the strongest association with
multiple sclerosis (MS). EBV is a ubiquitous double stranded DNA herpes virus that …

Epstein-Barr virus and multiple sclerosis

JD Lünemann, C Münz - Current neurology and neuroscience reports, 2007 - Springer
Epstein-Barr virus (EBV) is one of the most common and successful human viruses, infecting
more than 90% of the world's adult population. Despite its strong tumorigenic potential, most …

Epstein–Barr virus and multiple sclerosis: moving from questions of association to questions of mechanism

OG Thomas, A Rickinson… - Clinical & Translational …, 2023 - Wiley Online Library
Abstract The link between Epstein–Barr virus (EBV) and multiple sclerosis (MS) has puzzled
researchers since it was first discovered over 40 years ago. Until that point, EBV was …

[HTML][HTML] Epstein-Barr virus and multiple sclerosis: a convoluted interaction and the opportunity to unravel predictive biomarkers

OD Ortega-Hernandez, EM Martínez-Cáceres… - International Journal of …, 2023 - mdpi.com
Since the early 1980s, Epstein-Barr virus (EBV) infection has been described as one of the
main risk factors for developing multiple sclerosis (MS), and recently, new epidemiological …

[HTML][HTML] Gammaherpesvirus latency accentuates EAE pathogenesis: relevance to Epstein-Barr virus and multiple sclerosis

C Casiraghi, I Shanina, S Cho, ML Freeman… - PLoS …, 2012 - journals.plos.org
Epstein-Barr virus (EBV) has been identified as a putative environmental trigger of multiple
sclerosis (MS), yet EBV's role in MS remains elusive. We utilized murine gamma herpesvirus …

[HTML][HTML] Latent virus infection upregulates CD40 expression facilitating enhanced autoimmunity in a model of multiple sclerosis

C Casiraghi, A Citlali Márquez, I Shanina… - Scientific reports, 2015 - nature.com
Epstein-Barr virus (EBV) has been identified as a putative environmental trigger of multiple
sclerosis (MS) by multiple groups working worldwide. Previously, we reported that when …

Viral pathophysiology of multiple sclerosis: A role for Epstein-Barr virus infection?

AH Maghzi, M Marta, I Bosca, M Etemadifar, R Dobson… - Pathophysiology, 2011 - Elsevier
Multiple sclerosis (MS) is the most common inflammatory demyelinating and degenerative
disease of the CNS. The cause of MS is unknown but environmental risk factors are …

[HTML][HTML] Multiple sclerosis-like symptoms in mice are driven by latent γHerpesvirus-68 infected b cells

AC Márquez, I Shanina, MS Horwitz - Frontiers in Immunology, 2020 - frontiersin.org
Multiple sclerosis (MS) is caused by a combination of genetic and environmental factors. It is
believed that previous infection with Epstein Barr Virus (EBV) plays an important role in the …