[HTML][HTML] Drug databases and their contributions to drug repurposing

Y Masoudi-Sobhanzadeh, Y Omidi, M Amanlou… - Genomics, 2020 - Elsevier
Drug repurposing is an interesting field in the drug discovery scope because of reducing
time and cost. It is also considered as an appropriate method for finding medications for …

Exploration of databases and methods supporting drug repurposing: a comprehensive survey

Z Tanoli, U Seemab, A Scherer… - Briefings in …, 2021 - academic.oup.com
Drug development involves a deep understanding of the mechanisms of action and possible
side effects of each drug, and sometimes results in the identification of new and unexpected …

An analytical review of computational drug repurposing

SS Sadeghi, MR Keyvanpour - IEEE/ACM transactions on …, 2019 - ieeexplore.ieee.org
Drug repurposing is a vital function in pharmaceutical fields and has gained popularity in
recent years in both the pharmaceutical industry and research community. It refers to the …

Literature-based discovery of new candidates for drug repurposing

HT Yang, JH Ju, YT Wong, I Shmulevich… - Briefings in …, 2017 - academic.oup.com
Drug development is an expensive and time-consuming process; these could be reduced if
the existing resources could be used to identify candidates for drug repurposing. This study …

[HTML][HTML] DrugRep: an automatic virtual screening server for drug repurposing

J Gan, J Liu, Y Liu, S Chen, W Dai, ZX Xiao… - Acta Pharmacologica …, 2023 - nature.com
Computationally identifying new targets for existing drugs has drawn much attention in drug
repurposing due to its advantages over de novo drugs, including low risk, low costs, and …

A new computational drug repurposing method using established disease–drug pair knowledge

N Saberian, A Peyvandipour, M Donato, S Ansari… - …, 2019 - academic.oup.com
Motivation Drug repurposing is a potential alternative to the classical drug discovery
pipeline. Repurposing involves finding novel indications for already approved drugs. In this …

Computational methods for drug repurposing

P Sanseau, J Koehler - Briefings in bioinformatics, 2011 - academic.oup.com
Repurposing marketed drugs or compounds in development for alternative indications is not
new in the pharmaceutical industry. It is in fact quite common but it has been mostly done by …

DrugR+: a comprehensive relational database for drug repurposing, combination therapy, and replacement therapy

Y Masoudi-Sobhanzadeh, Y Omidi, M Amanlou… - Computers in biology …, 2019 - Elsevier
Drug repurposing or repositioning, which introduces new applications of the existing drugs,
is an emerging field in drug discovery scope. To enhance the success rate of the research …

Drug repurposing: a promising tool to accelerate the drug discovery process

V Parvathaneni, NS Kulkarni, A Muth, V Gupta - Drug discovery today, 2019 - Elsevier
Highlights•There is an emerging need for new therapies for rare diseases in a shorter time
frame.•Drug repurposing could arise from serendipitous observations or exploiting side …

Drug repurposing from the perspective of pharmaceutical companies

Y Cha, T Erez, IJ Reynolds, D Kumar… - British journal of …, 2018 - Wiley Online Library
Drug repurposing holds the potential to bring medications with known safety profiles to new
patient populations. Numerous examples exist for the identification of new indications for …