Phosphorylation of TRPV1 S801 contributes to modality-specific hyperalgesia in mice
J Joseph, L Qu, S Wang, M Kim, D Bennett… - Journal of …, 2019 - Soc Neuroscience
Transient receptor potential vanilloid subtype 1 (TRPV1) is a nonselective cationic channel
activated by painful stimuli such as capsaicin and noxious heat, and enriched in sensory …
activated by painful stimuli such as capsaicin and noxious heat, and enriched in sensory …
Distinctive changes in plasma membrane phosphoinositides underlie differential regulation of TRPV1 in nociceptive neurons
Transient Receptor Potential Vanilloid 1 (TRPV1) is a polymodal, Ca2+-permeable cation
channel crucial to regulation of nociceptor responsiveness. Sensitization of TRPV1 by G …
channel crucial to regulation of nociceptor responsiveness. Sensitization of TRPV1 by G …
TRPV1 gain-of-function mutation impairs pain and itch sensations in mice
L Duo, L Hu, N Tian, G Cheng, H Wang, Z Lin… - Molecular …, 2018 - journals.sagepub.com
Transient receptor potential vanilloid 1 (TRPV1) is a non-selective cation channel, which can
detect various noxious stimuli that cause pain, inflammation, hyperalgesia, and itch. TRPV1 …
detect various noxious stimuli that cause pain, inflammation, hyperalgesia, and itch. TRPV1 …
Rapid, opioid-sensitive mechanisms involved in transient receptor potential vanilloid 1 sensitization
I Vetter, W Cheng, M Peiris, BD Wyse… - Journal of Biological …, 2008 - ASBMB
TRPV1 is a nociceptive, Ca 2+-selective ion channel involved in the development of several
painful conditions. Sensitization of TRPV1 responses by cAMP-dependent PKA crucially …
painful conditions. Sensitization of TRPV1 responses by cAMP-dependent PKA crucially …
Role of Src kinase in regulating protein kinase C mediated phosphorylation of TRPV1
GL Robilotto, DP Mohapatra… - … Journal of Pain, 2022 - Wiley Online Library
Background Transient receptor potential vanilloid‐1 (TRPV1), activated by heat, acidic pH,
endogenous vanilloids and capsaicin, is essential for thermal hyperalgesia. Under …
endogenous vanilloids and capsaicin, is essential for thermal hyperalgesia. Under …
Coexpression and activation of TRPV1 suppress the activity of the KCNQ2/3 channel
XF Zhang, P Han, TR Neelands… - Journal of General …, 2011 - rupress.org
Transient receptor potential vanilloid 1 (TRPV1) is a ligand-gated nonselective cation
channel expressed predominantly in peripheral nociceptors. By detecting and integrating …
channel expressed predominantly in peripheral nociceptors. By detecting and integrating …
Targeting the transient receptor potential vanilloid type 1 (TRPV1) assembly domain attenuates inflammation-induced hypersensitivity
R Flynn, K Chapman, M Iftinca, R Aboushousha… - Journal of Biological …, 2014 - ASBMB
The transient receptor potential channel vanilloid type 1 (TRPV1) is a non-selective cation
channel expressed in sensory neurons of the dorsal root and trigeminal ganglia. TRPV1 is a …
channel expressed in sensory neurons of the dorsal root and trigeminal ganglia. TRPV1 is a …
Modulation of transient receptor vanilloid 1 activity by transient receptor potential ankyrin 1
V Spahn, C Stein, C Zöllner - Molecular pharmacology, 2014 - ASPET
Transient receptor potential vanilloid 1 (TRPV1) is a nonselective ligand-gated cation
channel responding to noxious heat, protons, and chemicals such as capsaicin. TRPV1 is …
channel responding to noxious heat, protons, and chemicals such as capsaicin. TRPV1 is …
TRPV1 is important for mechanical and heat sensitivity in uninjured animals and development of heat hypersensitivity after muscle inflammation
RY Walder, R Radhakrishnan, L Loo, LA Rasmussen… - PAIN®, 2012 - Elsevier
Inflammatory thermal hyperalgesia is principally mediated through transient receptor
potential vanilloid 1 (TRPV1) channels, as demonstrated by prior studies using models of …
potential vanilloid 1 (TRPV1) channels, as demonstrated by prior studies using models of …
Modulation of transient receptor potential Vanilloid 4-mediated membrane currents and synaptic transmission by protein kinase C
DS Cao, SQ Yu, LS Premkumar - Molecular pain, 2009 - journals.sagepub.com
Background Transient receptor potential Vanilloid (TRPV) receptors are involved in
nociception and are expressed predominantly in sensory neurons. TRPV1, a non-selective …
nociception and are expressed predominantly in sensory neurons. TRPV1, a non-selective …