Astrocytes as Drivers and Disruptors of Behavior: New Advances in Basic Mechanisms and Therapeutic Targeting

D Barnett, K Bohmbach, V Grelot, A Charlet… - Journal of …, 2023 - Soc Neuroscience
Astrocytes are emerging as key regulators of cognitive function and behavior. This review
highlights some of the latest advances in the understanding of astrocyte roles in different …

Deciphering the star codings: astrocyte manipulation alters mouse behavior

K Park, SJ Lee - Experimental & Molecular Medicine, 2020 - nature.com
Astrocytes occupy a vast area within the central nervous system (CNS). Despite their
abundance, the functional role of astrocytes in vivo has only begun to be uncovered …

From synapses to circuits, astrocytes regulate behavior

KA Lyon, NJ Allen - Frontiers in neural circuits, 2022 - frontiersin.org
Astrocytes are non-neuronal cells that regulate synapses, neuronal circuits, and behavior.
Astrocytes ensheath neuronal synapses to form the tripartite synapse where astrocytes …

Astrocyte function from information processing to cognition and cognitive impairment

M Santello, N Toni, A Volterra - Nature neuroscience, 2019 - nature.com
Astrocytes serve important roles that affect recruitment and function of neurons at the local
and network levels. Here we review the contributions of astrocyte signaling to synaptic …

Astrocytes in human central nervous system diseases: a frontier for new therapies

A Verkhratsky, A Butt, B Li, P Illes, R Zorec… - … and Targeted Therapy, 2023 - nature.com
Astroglia are a broad class of neural parenchymal cells primarily dedicated to homoeostasis
and defence of the central nervous system (CNS). Astroglia contribute to the …

Astrocytes as new targets to improve cognitive functions

G Dallérac, N Rouach - Progress in neurobiology, 2016 - Elsevier
Astrocytes are now viewed as key elements of brain wiring as well as neuronal
communication. Indeed, they not only bridge the gap between metabolic supplies by blood …

Astrocytes as master modulators of neural networks: Synaptic functions and disease‐associated dysfunction of astrocytes

JA Stogsdill, CC Harwell… - Annals of the New York …, 2023 - Wiley Online Library
Astrocytes are the most abundant glial cell type in the central nervous system and are
essential to the development, plasticity, and maintenance of neural circuits. Astrocytes are …

Astroglia as a cellular target for neuroprotection and treatment of neuro‐psychiatric disorders

B Liu, AG Teschemacher, S Kasparov - Glia, 2017 - Wiley Online Library
Astrocytes are key homeostatic cells of the central nervous system. They cooperate with
neurons at several levels, including ion and water homeostasis, chemical signal …

Molecular approaches for manipulating astrocytic signaling in vivo

AX Xie, J Petravicz, KD McCarthy - Frontiers in cellular neuroscience, 2015 - frontiersin.org
Astrocytes are the predominant glial type in the central nervous system and play important
roles in assisting neuronal function and network activity. Astrocytes exhibit complex …

Astrocytic regulation of neural circuits underlying behaviors

SN Hwang, JS Lee, K Seo, H Lee - Cells, 2021 - mdpi.com
Astrocytes, characterized by a satellite-like morphology, are the most abundant type of glia
in the central nervous system. Their main functions have been thought to be limited to …