As nanocarriers (NCs) can improve the solubility of drugs, prevent their degradation by
gastrointestinal (GI) enzymes and promote their transport across the mucus gel layer and …

In particular since the last two decades there is constantly increasing interest in nanocarrier
systems. They are utilized in order to overcome the major challenges being associated with …

The chemical environment and enzymes in the gastrointestinal (GI) membrane limit the oral
absorption of some vitamins. The GI epithelium also contributes to the poor permeability of …

The present review provides an overview of nanotechnology-based strategies to overcome
various mucus gel barriers including the intestinal, nasal, ocular, vaginal, buccal and …

Although nanotechnology has been investigated during recent years to increase the
bioavailability and therapeutic effects of mucosal administrated drugs, numerous barriers …

Lipid-based nanocarriers have gained much interest as carriers of drugs with poor oral
bioavailability because of their remarkable advantages like low toxicity, affordable scale-up …

This article is aimed to overview the lipid-based nanostructures designed so far for the oral
administration of peptides and proteins, and to analyze the influence of their composition …

Enteral administration is the most convenient route despite the gastrointestinal physiological
barriers. Nanostructured lipid carriers (NLCs) have emerged as a promising strategy for …

The hydrophobic character of most drug molecules and their potential for degradation under
the hostile environment of the gastrointestinal tract (GIT) constitutes the main obstacle in the …

Oral delivery is the most accepted and economical route for drug administration and leads to
substantial reduction in dosing frequency. However, this route still remains a challenge for …