Background This work summarizes the efficiency, failures and adverse effects of oral
administration of ketamine at home for intractable pain. Methods This 5‐year retrospective …

Background There is no recommendation in Europe for the use of ketamine in patients with
chronic pain. The heterogeneity of practice highlights the need to seek the advice of experts …

Objectives Ketamine is used to treat chronic refractory pain. However, there are no scientific
guidelines for ketamine use in the Netherlands. The aim of this survey was to provide an …

The analgesic effect of ketamine is primarily based on the antagonism of the N-methyl-d-
aspartate (NMDA) receptor. Activation of NMDA receptors may play a crucial role in the …

2.1. Study design This prospective, multicenter, and observational study was conducted in
30 French pain clinics (Observational Ketamine And PaIn study Consortium). All included …

Ketamine has diverse effects that may be of relevance to chronic pain including: N-methyl-d-
aspartic acid, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, kainate, γ …

BACKGROUND: IV ketamine is widely used to treat patients with chronic pain, yet the long-
term impact remains uncertain. We synthesized evidence from randomized control trials to …

Objectives: Describe the mode of action of ketamine. Identify the indications for ketamine
use in the management of pain. Summarize the complications of ketamine use and potential …

Anecdotal reports suggest that the general anaesthetic drug ketamine, taken orally in low
doses, can give rise to some extra analgesia in patients with refractory neuropathic pain …

Background and objective: Enterally administered low-dose ketamine is being used
increasingly to treat pain states. However, suitable oral or sublingual formulations are not …