Background & Aims Interleukin (IL)-20 and IL-22 belong to the IL-10 family. IL-10 is a well-
documented anti-inflammatory cytokine while IL-22 is well known for epithelial protection …

Summary The cytokine interleukin-22 (IL-22) is primarily expressed by T helper 17 (Th17)
CD4+ T cells and is highly upregulated during chronic inflammatory diseases. IL-22 receptor …

Abstract Introduction Interleukin (IL)-22, originally referred to as IL-TIF for IL-10-related T cell-
derived inducible factor, is a member of the IL-10-like cytokine family. IL-22 is highly …

The three main causes of inflammation and chronic injury in the liver are viral hepatitis,
alcohol consumption, and non-alcoholic steatohepatitis, all of which can lead to liver fibrosis …

Abstract Interleukin 22 (IL-22), a member of the IL-10 cytokine family and is an emerging
CD4+ Th cytokine that plays an important role in anti-microbial defense, homeostasis and …

The liver is the major metabolic organ and is subjected to constant attacks from chronic viral
infection, uptake of therapeutic drugs, life behavior (alcoholic), and environmental …

The alarmin IL‐33 has been described to be upregulated in human and murine viral
hepatitis. However, the role of endogenous IL‐33 in viral hepatitis remains obscure. We …

Hepatitis B virus (HBV) infection remains a worldwide health problem, and is the major
cause of hepatitis, liver cirrhosis, and hepatocellular carcinoma. The innate and adaptive …

Abstract Background Interleukin-23 (IL-23) is required for T helper 17 (Th17) cell responses
and IL-17 production in hepatitis B virus infection. A previous study showed that the IL-23/IL …

BACKGROUND & AIMS: T-helper (Th) 17 cells that secrete interleukin (IL)-22 have
immunomodulatory and protective properties in the liver and other tissues. IL-22 induces …