A multi-host approach was followed to screen a library of 1201 signature-tagged deletion
strains of Cryptococcus neoformans mutants to identify previously unknown virulence …

Cryptococcus neoformans var. neoformans is an important opportunistic fungal pathogen of
patients whose immune system has been compromised due to viral infection, antineoplastic …

Compared to Cryptococcus neoformans, little is known about the virulence of the molecular
types in Cryptococcus gattii. We compared in vitro virulence factor production and survival …

Abstract Analysis of the molecular mechanisms by which a pathogen interacts with the
human host is most commonly performed using a mammalian model of infection. However …

Cryptococcus neoformans and Cryptococcus gattii are well-studied basidiomyceteous
yeasts that are capable of causing disease in healthy and immunocompromised people. The …

The human pathogenic fungus Cryptococcus neoformans is a global health concern.
Previous research in the field has focused on studies using reference strains to identify …

Cryptococcus neoformans is a fungal pathogen that causes disease in
immunocompromised individuals, especially in HIVC/AIDS patients, and organ transplant …

The fungal pathogen Cryptococcus neoformans has three major virulence factors: growth at
37° C, capsule synthesis, and melanin formation. Recently in Cell, Liu et al.(2008) employed …

Most cases of cryptococcosis are caused by Cryptococcus neoformans var. grubii (serotype
A), which is widespread in the environment, where it is primarily associated with pigeon …

Patient outcomes during infection are due to a complex interplay between the quality of
medical care, host immunity factors, and the infecting pathogen's characteristics. To probe …