Breaching multiple barriers: leukocyte motility through venular walls and the interstitium
S Nourshargh, PL Hordijk, M Sixt - Nature reviews Molecular cell …, 2010 - nature.com
The shuttling of leukocytes between the bloodstream and interstitial tissues involves different
locomotion strategies that are governed by locally presented soluble and cell-bound signals …
locomotion strategies that are governed by locally presented soluble and cell-bound signals …
[HTML][HTML] Leukocyte migration into inflamed tissues
S Nourshargh, R Alon - Immunity, 2014 - cell.com
Leukocyte migration through activated venular walls is a fundamental immune response that
is prerequisite to the entry of effector cells such as neutrophils, monocytes, and effector T …
is prerequisite to the entry of effector cells such as neutrophils, monocytes, and effector T …
Migration of leukocytes through the vessel wall and beyond
R Yadav, KY Larbi, RE Young… - Thrombosis and …, 2003 - thieme-connect.com
The migration of leukocytes from the vascular lumen to sites of infection and/or injury in the
extravascular tissue involves a series of sequential and coordinated molecular and cellular …
extravascular tissue involves a series of sequential and coordinated molecular and cellular …
Leukocyte migration in the interstitial space of non-lymphoid organs
Leukocyte migration through interstitial tissues is essential for mounting a successful
immune response. Interstitial motility is governed by a vast array of cell-intrinsic and cell …
immune response. Interstitial motility is governed by a vast array of cell-intrinsic and cell …
[HTML][HTML] Endothelial signaling in paracellular and transcellular leukocyte transmigration
ES Wittchen - Frontiers in bioscience: a journal and virtual library, 2009 - ncbi.nlm.nih.gov
As the primary physical barrier between blood and tissue compartments within the body,
blood vessel endothelial cells and integrity of the cell junctions connecting them must be …
blood vessel endothelial cells and integrity of the cell junctions connecting them must be …
Transmigration through venular walls: a key regulator of leukocyte phenotype and function
S Nourshargh, FM Marelli-Berg - Trends in immunology, 2005 - cell.com
Leukocyte transmigration is a key event in host defense. As well as delivering leukocytes to
sites of inflammation, this response also has an important role in immunity by regulating the …
sites of inflammation, this response also has an important role in immunity by regulating the …
Neutrophil recruitment under shear flow: it's all about endothelial cell rings and gaps
P Alcaide, S Auerbach, FW Luscinskas - Microcirculation, 2009 - Taylor & Francis
Leukocyte recruitment to tissues and organs is an essential component of host defense. The
molecular mechanisms controlling this process are complex and remain under active …
molecular mechanisms controlling this process are complex and remain under active …
Signaling in leukocyte transendothelial migration
JD Van Buul, PL Hordijk - Arteriosclerosis, thrombosis, and …, 2004 - Am Heart Assoc
Under a variety of (patho) physiological conditions, leukocytes will leave the bloodstream by
crossing the endothelial monolayer that lines the vessels and migrate into the underlying …
crossing the endothelial monolayer that lines the vessels and migrate into the underlying …
Endothelial signalling events during leukocyte transmigration
PL Hordijk - The FEBS journal, 2006 - Wiley Online Library
The notion that it takes two to tango is certainly true for leukocyte transendothelial migration.
A growing pallet of leukocyte adhesion‐induced signaling events in endothelial cells have …
A growing pallet of leukocyte adhesion‐induced signaling events in endothelial cells have …
LFA-1 and Mac-1 define characteristically different intralumenal crawling and emigration patterns for monocytes and neutrophils in situ
To exit blood vessels, most (∼ 80%) of the lumenally adhered monocytes and neutrophils
crawl toward locations that support transmigration. Using intravital confocal microscopy of …
crawl toward locations that support transmigration. Using intravital confocal microscopy of …