Abnormal plasma apolipoprotein levels are consistently implicated in CVD risk. Although
30% to 60% of their interindividual variability is genetic, common genetic variants explain …

Background Circulating lipoprotein lipids cause coronary heart disease (CHD). However,
the precise way in which one or more lipoprotein lipid-related entities account for this …

Plasma lipoprotein concentrations are associated with risk of coronary artery disease, a
leading cause of mortality and morbidity worldwide. Three new genome-wide association …

Background—Plasma levels of high-density lipoprotein cholesterol (HDL-C) are known to be
heritable, but only a fraction of the heritability is explained. We used a high-density …

Deep sequencing of genome-wide association signals promises to expand the catalogue of
variants responsible for serum lipid variation and, with a full catalogue of variants, we may …

Although common APOE genetic variation has a major influence on plasma LDL-
cholesterol, its role in affecting HDL-cholesterol and triglycerides is not well established …

For those who have witnessed the evolution of genetic association studies of plasma lipids
since 1983, the field has had its roller-coaster moments. The early high points followed from …

Apolipoproteins (APO proteins) are the lipoprotein family proteins that play key roles in
transporting lipoproteins all over the body. There are nearly more than twenty members …

BACKGROUND: Dyslipoproteinemia often involves simultaneous derangements of multiple
lipid traits. We aimed to evaluate the phenotypic and genetic characteristics of combined …

Background—Plasma lipid levels as well as coronary artery disease (CAD) have been
shown to be highly heritable with estimates ranging from 40% to 60%. However, top variants …