Background Recombinant pertussis vaccines inducing long-lasting immune responses
could help to control the rise in pertussis. We here report on persisting antibody responses 2 …

Background The immunogenicity of acellular pertussis vaccines and persistence of immunity
after vaccination might be improved by using genetically inactivated pertussis toxin (PTgen) …

Background Protection induced by acellular pertussis (aP) vaccines is partial and short-
lived, especially in teenagers, calling for novel immunization strategies. Methods We …

Background. We conducted a 5-year follow-up study on the persistence of pertussis-specific
antibody and cell-mediated immunity after booster immunization of adolescents aged 11–13 …

Introduction To reduce the pertussis disease burden, nowadays several countries
recommend acellular pertussis (aP) booster vaccinations for adults. We aimed to evaluate …

Pertussis is a highly contagious disease, for which periodic peaks in incidence and an
increasing number of outbreaks have been observed over the last decades. The reduced …

Background Increasing evidence shows that protection induced by acellular pertussis
vaccines is short-lived, requiring repeated booster vaccination to control pertussis disease …

Compared to whole cell pertussis (wcP) vaccines, acellular pertussis vaccines (aP) have a
better safety profile with lower reactogenicity, although their short and long-term efficacy was …

Introduction Pertussis is re-emerging worldwide, despite effective immunization programs for
infants and children. Epidemiological studies show a more limited duration of protection …

Background Over the last decades, pertussis showed periodic increases in its incidence
among adults, despite being a vaccine-preventable disease. Methods This phase III …