Mechanism and Therapeutic Prospect of miRNAs in Neurodegenerative Diseases

YM Ma, L Zhao - Behavioural Neurology, 2023 - Wiley Online Library
MicroRNAs (miRNAs) are the smallest class of noncoding RNAs, which widely exist in
animals and plants. They can inhibit translation or overexpression by combining with mRNA …

MicroRNAs: protective regulators for neuron growth and development

ZX Ma, Z Liu, HH Xiong, ZP Zhou… - Neural regeneration …, 2023 - journals.lww.com
MicroRNAs (miRNAs) play an important regulatory role in neuronal growth and
development. Different miRNAs target different genes to protect neurons in different ways …

[HTML][HTML] MicroRNA (miRNA) as a biomarker for diagnosis, prognosis, and therapeutics molecules in neurodegenerative disease

Z Alkhazaali-Ali, S Sahab-Negah… - Biomedicine & …, 2024 - Elsevier
Neurodegenerative diseases that include Alzheimer's disease (AD), amyotrophic lateral
sclerosis (ALS), Parkinson's disease (PD), Huntington's disease (HD), and multiple sclerosis …

Current Updates on the Role of MicroRNA in the Diagnosis and Treatment of Neurodegenerative Diseases

A Saleem, M Javed, M Furqan Akhtar… - Current Gene …, 2024 - ingentaconnect.com
Background: MicroRNAs (miRNA) are small noncoding RNAs that play a significant role in
the regulation of gene expression. The literature has explored the key involvement of …

Noncoding RNAs in neurodegenerative diseases

SD Rege, T Geetha, SR Pondugula… - International …, 2013 - Wiley Online Library
Noncoding RNAs are widely known for their various essential roles in the development of
central nervous system. It involves neurogenesis, neural stem cells generation, maintenance …

Regulatory triangle of neurodegeneration, adult neurogenesis and microRNAs

T Singh, A Jauhari, A Pandey, P Singh… - CNS & Neurological …, 2014 - ingentaconnect.com
MicroRNAs (miRNAs) have emerged as a new class of RNA molecules which are short in
length, less in number but play bigger role in regulation of cellular events. miRNAs keep …

MicroRNAs and molecular mechanisms of neurodegeneration

I Bicchi, F Morena, S Montesano, M Polidoro, S Martino - Genes, 2013 - mdpi.com
During the last few years microRNAs (miRNAs) have emerged as key mediators of post-
transcriptional and epigenetic regulation of gene expression. MiRNAs targets, identified …

The involvement of microRNAs in neurodegenerative diseases

S Maciotta, M Meregalli, Y Torrente - Frontiers in cellular …, 2013 - frontiersin.org
Neurodegenerative diseases (NDDs) originate from a loss of neurons in the central nervous
system and are severely debilitating. The incidence of NDDs increases with age, and they …

MicroRNAs in neurodegenerative diseases and their therapeutic potential

E Junn, MM Mouradian - Pharmacology & therapeutics, 2012 - Elsevier
MicroRNAs (miRNAs) are abundant, endogenous, short, noncoding RNAs that act as
important post-transcriptional regulators of gene expression by base-pairing with their target …

MicroRNA alteration, application as biomarkers, and therapeutic approaches in neurodegenerative diseases

TPN Nguyen, M Kumar, E Fedele, G Bonanno… - International journal of …, 2022 - mdpi.com
MicroRNAs (miRNAs) are essential post-transcriptional gene regulators involved in various
neuronal and non-neuronal cell functions and play a key role in pathological conditions …