WNT-5A plays critical roles in a myriad of processes from embryonic morphogenesis to the
maintenance of post-natal homeostasis. WNT-5A knock-out mice fail to survive and present …

Wnt5a is a representative ligand that activates the β‐catenin‐independent pathways.
Because the β‐catenin‐independent pathway includes multiple signalling cascades in …

WNT10B, a member of the WNT family of secreted glycoproteins, activates the WNT/β-
CATENIN signaling cascade to control proliferation, stemness, pluripotency, and cell fate …

Abstract WNT family member 4 (WNT4), which belongs to the conserved WNT protein family,
plays an important role in the development and differentiation of many cell types during the …

Wnt5a is involved in the activation of noncanonical Wnt signaling, including planar cell
polarity (PCP) and Wnt-Ca 2+ pathways. The Ror-family of receptor tyrosine kinases is …

The Wnt-β-catenin signaling pathway is an evolutionarily conserved cell-cell communication
system that is important for stem cell renewal, cell proliferation and cell differentiation both …

The WNT signal transduction cascade controls myriad biological phenomena throughout
development and adult life of all animals. In parallel, aberrant Wnt signaling underlies a …

A remarkable interdisciplinary effort has unraveled the WNT (Wingless and INT-1) signal
transduction cascade over the last two decades. Wnt genes encode small secreted proteins …

Wnt5a is involved in activating several noncanonical Wnt signaling pathways, which can
inhibit or activate canonical Wnt/β‐catenin signaling pathway in a receptor context …

Wnt/β-catenin signalling plays essential roles in embryonic development as well as tissue
homoeostasis in adults. Thus abnormal regulation of Wnt/β-catenin signalling is linked to a …