Optimization is a critical process in the development of nanoparticles to apprehend the
formulation variables and quality attributes. The purpose of this study was to evaluate the …

Objective: Quality is considered to be the major tool in pharmaceutical industry. Failures in
the quality of upcoming new chemical entities have been seen in the recent years due to …

Biodegradable nanoparticles (NPs) have gained tremendous interest for targeting
chemotherapeutic drugs to the tumor environment. Inspite of several advances sufficient …

Purpose The aim of this research was to develop and optimize a process for obtaining poly
ɛ-caprolactone (PCL) nanoparticles loaded with Uncaria tomentosa (UT) extract. Methods …

Context: Polymeric carrier systems of paclitaxel (PCT) offer advantages over only available
formulation Taxol® in terms of enhancing therapeutic efficacy and eliminating adverse …

Abstract Objective: Paclitaxel (PTX)-loaded polymer (Poly (lactic-co-glycolic acid), PLGA)-
based nanoformulation was developed with the objective of formulating cremophor EL-free …

The present study was aimed to fabricate Curcumin loaded Eudragit E 100 polymeric
nanoparticles and to study the effect of various manufacturing parameters on the average …

Background The overall objective was to prepare a highly accurate nanocarrier system of
mesalamine for the treatment of ulcerative colitis with increased therapeutic efficacy and …

Background: The Box–Behnken design of experiments (BBD) is a statistical modelling
technique that allows the determination of the significant factors in developing nanoparticles …

The isradipine is the potent anti hypertensive drug, which is matrix in polymeric nanoparticle
by using solvent evaporation method. In this work, 3-factor, 3-level Box-Behnken design was …