Stress-related disorders, such as anxiety, early life stress, and posttraumatic stress disorder
appear to be important factors in promoting alcoholism, as alcohol consumption can …

Acute and chronic stressors have been associated with alterations in mood and increased
anxiety that may eventually result in the development of stress-related psychiatric disorders …

Genetic and environmental factors play a role in the development of alcoholism. Whole-
genome expression profiling has highlighted the importance of several genes that may …

Alcoholism is a complex brain disease characterized by three distinct stages of the addiction
cycle that manifest as neuroadaptive changes in the brain. One such stage of the addiction …

This work highlights recent studies in epigenetic mechanisms that play a role in alcoholism,
which is a complex multifactorial disorder. There is a large body of evidence showing that …

This review deals with the recent developments on the epigenetic effects of ethanol. A large
body of data have come from studies in liver and in neuronal systems and involve post …

The chronic high-level alcohol consumption seen in alcoholism leads to dramatic effects on
the hippocampus, including decreased white matter, loss of oligodendrocytes and other glial …

Metabolites, including those generated during ethanol metabolism, can impact disease
states by binding to transcription factors and/or modifying chromatin structure, thereby …

Chronic alcohol use and abuse result in widespread changes to gene expression, some of
which contribute to the development of alcohol-use disorders (AUD). Gene expression is …

Alterations in gene expression are implicated in the pathogenesis of several
neuropsychiatrie disorders, including drug addiction and depression, increasing evidence …