Guidance for the evaluation and treatment of hereditary and acquired thrombophilia

SM Stevens, SC Woller, KA Bauer, R Kasthuri… - Journal of thrombosis …, 2016 - Springer
Thrombophilias are hereditary and/or acquired conditions that predispose patients to
thrombosis. Testing for thrombophilia is commonly performed in patients with venous …

Screening for inherited thrombophilia: indications and therapeutic implications

V De Stefano, E Rossi, K Paciaroni, G Leone - haematologica, 2002 - haematologica.org
BACKGROUND AND OBJECTIVES: In recent years knowledge concerning inherited and
acquired causes of thrombophilia has increased greatly. The most common inherited traits …

Inherited thrombophilias in pregnant patients: detection and treatment paradigm

CJ Lockwood - Obstetrics & Gynecology, 2002 - journals.lww.com
Inherited thrombophilias are the leading cause of maternal thromboembolism and are
associated with an increased risk of certain adverse pregnancy outcomes including second …

Thrombophilia: common questions on laboratory assessment and management

JA Heit - ASH Education Program Book, 2007 - ashpublications.org
Thrombophilia is an inherited or acquired predisposition to thrombosis. This article reviews
the clinical manifestations of thrombophilia and addresses common questions on laboratory …

Inherited thrombophilia: a double-edged sword

S Middeldorp - Hematology 2014, the American Society of …, 2016 - ashpublications.org
Inherited thrombophilia is a blood coagulation disorder that increases the risk for venous
thromboembolism (VTE). During the last decades, the practice of testing has evolved from …

Thrombophilia: clinical–practical aspects

S Moll - Journal of thrombosis and thrombolysis, 2015 - Springer
No consensus exists as to who should be tested for thrombophilia, mainly due to the lack of
good quality clinical outcome data in relationship to presence or absence of a given …

The inherited thrombophilias: genetics, epidemiology, and laboratory evaluation

GS Buchanan, GM Rodgers, DW Branch - Best Practice & Research …, 2003 - Elsevier
It is now possible to identify a predisposing thrombophilic condition for venous thrombosis in
well over half of the cases. Certain thrombophilia diagnoses have a major impact on …

Inherited thrombophilia: part 1

DA Lane, PM Mannucci, KA Bauer… - Thrombosis and …, 1996 - thieme-connect.com
Although familial clustering of venous thromboembolic events was observed at the start of
this century, it was not until the late nineteenseventies before our insight into the …

Pros and cons of thrombophilia testing: cons

SJ Machin - Journal of Thrombosis and Haemostasis, 2003 - jthjournal.org
Thrombophilia is generally defined as an inherited disorder of the hemostatic system that
results in an increased risk of venous thromboembolism (VTE). There are several well …

Evidence-based indications for thrombophilia screening

Lindhoff-Last, Luxembourg - Vasa, 2008 - econtent.hogrefe.com
Thrombophilic defects have been shown to be associated with an increased risk of venous
thrombosis, fetal loss, and gestational complications. The knowledge about the clinical …