[HTML][HTML] Role of induced programmed cell death in the chemopreventive potential of apigenin

JY Jang, B Sung, ND Kim - International Journal of Molecular Sciences, 2022 - mdpi.com
The flavonoid apigenin (4′, 5, 7-trihydroxyflavone), which is one of the most widely
distributed phytochemicals in the plant kingdom, is one of the most thoroughly investigated …

[HTML][HTML] Apigenin induces both intrinsic and extrinsic pathways of apoptosis in human colon carcinoma HCT-116 cells

B Wang, XH Zhao - Oncology reports, 2017 - spandidos-publications.com
Apigenin is one of the plant-originated flavones with anticancer activities. In this study,
apigenin was assessed for its in vitro effects on a human colon carcinoma line (HCT‑116 …

Apigenin induces apoptosis in human lung cancer H460 cells through caspase-and mitochondria-dependent pathways

HF Lu, YJ Chie, MS Yang, KW Lu… - Human & …, 2011 - journals.sagepub.com
Apigenin (4, 5, 7-trihydroxyflavone), a promising chemopreventive agent presented in fruits
and vegetables, has been shown to induce cell cycle arrest and apoptosis in many types of …

[HTML][HTML] Apigenin role as cell-signaling pathways modulator: implications in cancer prevention and treatment

Z Javed, H Sadia, MJ Iqbal, S Shamas, K Malik… - Cancer Cell …, 2021 - Springer
Cancer is a complex disease orchestrated by various extrinsic and intrinsic pathways. In
recent years, there has been a keen interest towards the development of natural extracts …

[HTML][HTML] Role of apigenin in cancer prevention via the induction of apoptosis and autophagy

B Sung, HY Chung, ND Kim - Journal of cancer prevention, 2016 - ncbi.nlm.nih.gov
Abstract Apigenin (4′, 5, 7-trihydroxyflavone) is a flavonoid commonly found in many fruits
and vegetables such as parsley, chamomile, celery, and kumquats. In the last few decades …

Apigenin, a dietary flavonoid, induces apoptosis, DNA damage, and oxidative stress in human breast cancer MCF-7 and MDA MB-231 cells

I Vrhovac Madunić, J Madunić, M Antunović… - Naunyn-Schmiedeberg's …, 2018 - Springer
Apigenin is found in several dietary plant foods such as vegetables and fruits. To investigate
potential anticancer properties of apigenin on human breast cancer, ER-positive MCF-7 and …

Apigenin's anticancer properties and molecular mechanisms of action: Recent advances and future prospectives

JMM Salmani, XP Zhang, JA Jacob… - Chinese journal of natural …, 2017 - Elsevier
Cancer is a major health concern and leading burden on economy worldwide. An increasing
effort is devoted to isolation and development of plant-derived dietary components as …

Induction of cancer cell death by apigenin: a review on different cell death pathways

P Amini, R Moazamiyanfar, MS Dakkali… - Mini reviews in …, 2023 - ingentaconnect.com
Induction of cell death and inhibition of cell proliferation in cancer have been set as some of
the main goals in anti-tumor therapy. Cancer cell resistance leads to less efficient cancer …

Apigenin as an anticancer agent

M Imran, T Aslam Gondal, M Atif… - Phytotherapy …, 2020 - Wiley Online Library
Apigenin is an edible plant‐derived flavonoid that has been reported as an anticancer agent
in several experimental and biological studies. It exhibits cell growth arrest and apoptosis in …

Deciphering the modulatory role of apigenin targeting oncogenic pathways in human cancers

P Pandey, F Khan, TK Upadhyay - Chemical Biology & Drug …, 2023 - Wiley Online Library
Cancer is a complicated malignancy controlled by numerous intrinsic and extrinsic
pathways. There has been a significant increase in interest in recent years in the elucidation …