[HTML][HTML] Regulation of intestinal barrier function by microbial metabolites

S Ghosh, CS Whitley, B Haribabu, VR Jala - Cellular and molecular …, 2021 - Elsevier
The human gastrointestinal tract (GI) harbors a diverse population of microbial life that
continually shapes host pathophysiological responses. Despite readily available abundant …

Pathways and functions of gut microbiota metabolism impacting host physiology

S Krishnan, N Alden, K Lee - Current opinion in biotechnology, 2015 - Elsevier
Highlights•Intestinal microbiota performs diverse metabolic functions essential for host
physiology.•Small molecule products of microbiota metabolism act as nutrients and …

Deciphering the chemical lexicon of host–gut microbiota interactions

GR Nicolas, PV Chang - Trends in pharmacological sciences, 2019 - cell.com
The human intestine harbors an immense, diverse, and critical population of bacteria that
has effects on numerous aspects of host physiology, immunity, and disease. Emerging …

Chemical communication in the gut: Effects of microbiota-generated metabolites on gastrointestinal bacterial pathogens

SL Vogt, J Peña-Díaz, BB Finlay - Anaerobe, 2015 - Elsevier
Gastrointestinal pathogens must overcome many obstacles in order to successfully colonize
a host, not the least of which is the presence of the gut microbiota, the trillions of commensal …

Host–microbe interactions shaping the gastrointestinal environment

GE Kaiko, TS Stappenbeck - Trends in immunology, 2014 - cell.com
Tremendous advances have been made in mapping the complexity of the human gut
microbiota in both health and disease states. These analyses have revealed that, rather than …

Manipulation of epithelial integrity and mucosal immunity by host and microbiota‐derived metabolites

H Kayama, K Takeda - European journal of immunology, 2020 - Wiley Online Library
The human intestinal tract contains a large number of microbes, their metabolites, and
potentially harmful food antigens. The intestinal epithelium separates the mucosa where …

Bridging intestinal immunity and gut microbiota by metabolites

G Wang, S Huang, Y Wang, S Cai, H Yu, H Liu… - Cellular and Molecular …, 2019 - Springer
The gastrointestinal tract is the site of nutrient digestion and absorption and is also colonized
by diverse, highly mutualistic microbes. The intestinal microbiota has diverse effects on the …

Microbial contribution to the human metabolome: implications for health and disease

W Van Treuren, D Dodd - Annual Review of Pathology …, 2020 - annualreviews.org
The human gastrointestinal tract is home to an incredibly dense population of microbes.
These microbes employ unique strategies to capture energy in this largely anaerobic …

Microbial metabolites and intestinal stem cells tune intestinal homeostasis

PY Xing, S Pettersson, P Kundu - Proteomics, 2020 - Wiley Online Library
Microorganisms that colonize the gastrointestinal tract, collectively known as the gut
microbiota, are known to produce small molecules and metabolites that significantly …

Microbial metabolites determine host health and the status of some diseases

P Sittipo, J Shim, YK Lee - International journal of molecular sciences, 2019 - mdpi.com
The gastrointestinal (GI) tract is a highly complex organ composed of the intestinal
epithelium layer, intestinal microbiota, and local immune system. Intestinal microbiota …