Immunoengineering strategies to enhance vascularization and tissue regeneration

J Zarubova, MM Hasani-Sadrabadi, R Ardehali… - Advanced drug delivery …, 2022 - Elsevier
Immune cells have emerged as powerful regulators of regenerative as well as pathological
processes. The vast majority of regenerative immunoengineering efforts have focused on …

Modulation of the activity of stem and progenitor cells by immune cells

YK Alshoubaki, B Nayer, S Das… - Stem Cells …, 2022 - academic.oup.com
Numerous components of the immune system, including inflammatory mediators, immune
cells and cytokines, have a profound modulatory effect on the homeostatic regulation and …

Manipulating the intersection of angiogenesis and inflammation

BJ Kwee, DJ Mooney - Annals of biomedical engineering, 2015 - Springer
There exists a critical need to develop strategies that promote blood vessel formation
(neovascularization) in virtually all tissue engineering and regenerative medicine efforts …

Drug delivery and tissue engineering to promote wound healing in the immunocompromised host: Current challenges and future directions

AM Tatara, DP Kontoyiannis, AG Mikos - Advanced drug delivery reviews, 2018 - Elsevier
As regenerative medicine matures as a field, more promising technologies are being
translated from the benchtop to the clinic. However, many of these strategies are designed …

Harnessing the innate and adaptive immune system for tissue repair and regeneration: Considering more than macrophages

LC Shanley, OR Mahon, DJ Kelly, A Dunne - Acta Biomaterialia, 2021 - Elsevier
Tissue healing and regeneration is a complex, choreographed, spatiotemporal process
involving a plethora of cell types, the activity of which is stringently regulated in order for …

Biomimetic immunomodulation strategies for effective tissue repair and restoration

RA Villarreal-Leal, GD Healey, B Corradetti - Advanced drug delivery …, 2021 - Elsevier
Inflammation plays a central role in wound healing following injury or disease and is
mediated by a precise cascade of cellular and molecular events. Unresolved inflammatory …

Harnessing biomaterials for lymphatic system modulation

L Alderfer, E Hall, D Hanjaya-Putra - Acta biomaterialia, 2021 - Elsevier
The lymphatic system plays an integral part in regulating immune cell trafficking and the
transport of macromolecules. However, its influence on disease progression and drug …

Immune modulation of stem cells and regeneration

AB Aurora, EN Olson - Cell stem cell, 2014 - cell.com
The immune system, best known as the first line of defense against invading pathogens, is
integral to tissue development, homeostasis, and wound repair. In recent years, there has …

Tissue engineering of endothelial cells and the immune response

H Methe, ER Edelman - Transplantation proceedings, 2006 - Elsevier
BACKGROUND: While tissue engineering offers promise for organ and tissue
transplantation, it can also be used to examine transplant and immune biology. Endothelial …

Engineering immunomodulatory biomaterials to tune the inflammatory response

A Vishwakarma, NS Bhise, MB Evangelista… - Trends in …, 2016 - cell.com
Current state-of-the-art biomedical implants and tissue engineering methods promise
technologies to improve or even restore the function of diseased organs. However, one of …