Quantification of spatially localized MRS by a novel deep learning approach without spectral fitting

Y Zhang, J Shen - Magnetic resonance in medicine, 2023 - Wiley Online Library
Purpose To propose a novel end‐to‐end deep learning model to quantify absolute
metabolite concentrations from in vivo J‐point resolved spectroscopy (JPRESS) without …

Intact metabolite spectrum mining by deep learning in proton magnetic resonance spectroscopy of the brain

HH Lee, H Kim - Magnetic resonance in medicine, 2019 - Wiley Online Library
Purpose To develop a robust method for brain metabolite quantification in proton magnetic
resonance spectroscopy (1H‐MRS) using a convolutional neural network (CNN) that maps …

Deep learning‐based target metabolite isolation and big data‐driven measurement uncertainty estimation in proton magnetic resonance spectroscopy of the brain

HH Lee, H Kim - Magnetic resonance in medicine, 2020 - Wiley Online Library
Purpose The aim of this study was to develop a method for metabolite quantification with
simultaneous measurement uncertainty estimation in deep learning‐based proton magnetic …

[HTML][HTML] Physics-informed deep learning approach to quantification of human brain metabolites from magnetic resonance spectroscopy data

A Shamaei, J Starcukova, Z Starcuk Jr - Computers in Biology and Medicine, 2023 - Elsevier
Purpose While the recommended analysis method for magnetic resonance spectroscopy
data is linear combination model (LCM) fitting, the supervised deep learning (DL) approach …

Improved localization, spectral quality, and repeatability with advanced MRS methodology in the clinical setting

DK Deelchand, K Kantarci, G Öz - Magnetic resonance in …, 2018 - Wiley Online Library
Purpose To investigate the utility of an advanced magnetic resonance spectroscopy (MRS)
protocol in the clinical setting, and to compare the localization accuracy, spectral quality, and …

Magnetic Resonance Spectroscopy Quantification Aided by Deep Estimations of Imperfection Factors and Macromolecular Signal

D Chen, M Lin, H Liu, J Li, Y Zhou… - IEEE Transactions …, 2024 - ieeexplore.ieee.org
Objective: Magnetic Resonance Spectroscopy (MRS) is an important technique for
biomedical detection. However, it is challenging to accurately quantify metabolites with …

ProFit‐1D—A 1D fitting software and open‐source validation data sets

T Borbath, S Murali‐Manohar, J Dorst… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose Accurate and precise MRS fitting is crucial for metabolite concentration
quantification of 1H‐MRS spectra. LCModel, a spectral fitting software, has shown to have …

Assessment of measurement precision in single‐voxel spectroscopy at 7 T: Toward minimal detectable changes of metabolite concentrations in the human brain in …

LT Riemann, CS Aigner, SLR Ellison… - Magnetic …, 2022 - Wiley Online Library
Purpose To introduce a study design and statistical analysis framework to assess the
repeatability, reproducibility, and minimal detectable changes (MDCs) of metabolite …

Bayesian deep learning–based 1H‐MRS of the brain: Metabolite quantification with uncertainty estimation using Monte Carlo dropout

HH Lee, H Kim - Magnetic Resonance in Medicine, 2022 - Wiley Online Library
Purpose To develop a Bayesian convolutional neural network (BCNN) with Monte Carlo
dropout sampling for metabolite quantification with simultaneous uncertainty estimation in …

Investigating the effect of spectral linewidth on metabolite measurement bias in short-TE MRS

J Near - Proc Int Soc Magn Reson Med, 2014 - archive.ismrm.org
It has been shown previously that when LCModel is used for spectral quantification of short-
TE MRS data, increasing spectral linewidth results in a decrease in the estimated …