Cancer is a multi-step process where normal cells become transformed, grow, and may
disseminate to establish new lesions within the body. In recent years, the physical properties …

The physical sciences and engineering have introduced novel perspectives into the study of
cancer through model systems, tools, and metrics that enable integration of basic science …

As tumor cells metastasize from the primary tumor location to a distant secondary site, they
encounter an array of biologically and physically heterogeneous microenvironments. While …

The microenvironment in a solid tumor includes a multitude of cell types, matrix proteins, and
growth factors that profoundly influence cancer cell mechanics by providing both physical …

Highlights•Physical cues from the tumor microenvironment strongly affect cancer cell
behavior.•Novel techniques increasingly help to capture those cues in vitro.•Mechanisms for …

Cancer is a complex and dynamic disease that is aberrant both biologically and physically.
There is growing appreciation that physical abnormalities with both cancer cells and their …

Eight classical hallmarks of cancer have been proposed and are well-defined by using
biochemical or molecular genetic methods, but are not yet precisely defined by cellular …

Metastasis is a complex, multistep process responsible for> 90% of cancer-related deaths. In
addition to genetic and external environmental factors, the physical interactions of cancer …

Targeting Biophysical Cues: a Niche Approach to Study, Diagnose, and Treat Cancer: Trends
in Cancer Skip to Main Content Advertisement Trends in Cancer This journal offers authors …

Cell mechanics research is rapidly expanding within the cancer community. Its increasing
recognition within cancer biology likely stems from the fact that metastasis is an inherently …