Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss and multiple cognitive impairments. AD is marked by multiple cellular changes …

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss and multiple cognitive impairments. Several decades of intense research have …

Neurons affected in Alzheimer's disease (AD) experience mitochondrial dysfunction and a
bioenergetic deficit that occurs early and promotes the disease-defining amyloid beta …

The pathology of Alzheimer's disease (AD) is characterized by amyloid plaques (aggregates
of amyloid-β (Aβ)) and neurofibrillary tangles (aggregates of tau) and is accompanied by …

Aging is the time-dependent process that all living organisms go through characterized by
declining physiological function due to alterations in metabolic and molecular pathways …

Accumulation of damaged mitochondria is a hallmark of aging and age-related
neurodegeneration, including Alzheimer's disease (AD). The molecular mechanisms of …

The histopathological characteristics of Alzheimer's disease (AD) are amyloid-β (Aβ)
containing plaques and neurofibrillary tangles (NFTs) as well as neuronal and synaptic loss …

Alzheimer's disease (AD) is a progressive, mental illness without cure. Several years of
intense research on postmortem AD brains, cell and mouse models of AD have revealed …

Mitochondrial dysfunctions are central players in Alzheimer's disease (AD). In addition,
impairments in mitophagy, the process of selective mitochondrial degradation by autophagy …

Significance: Synaptic degeneration, an early pathological feature in Alzheimer's disease
(AD), is closely correlated to impaired cognitive function and memory loss. Recent studies …