Purification, physicochemical properties, and statistical optimization of fibrinolytic enzymes especially from fermented foods: a comprehensive review

AMM Ali, SCB Bavisetty - International Journal of Biological …, 2020 - Elsevier
Fibrinolytic enzymes are proteases responsible for cleavage of fibrin mesh in thrombus clots,
which are the primary causative agents in cardiovascular diseases. Developing safe …

Fibrinolytic enzymes in Asian traditional fermented foods

Y Mine, AHK Wong, B Jiang - Food Research International, 2005 - Elsevier
Cardiovascular diseases, such as heart attack and stroke, are the leading causes of death in
North America. According to data provided by the World Health Organization in 2000, heart …

Statistical Optimization of Fibrinolytic Enzyme Production Using Agroresidues by Bacillus cereus IND1 and Its Thrombolytic Activity In Vitro

P Vijayaraghavan… - BioMed research …, 2014 - Wiley Online Library
A potent fibrinolytic enzyme‐producing Bacillus cereus IND1 was isolated from the Indian
food, rice. Solid‐state fermentation was carried out using agroresidues for the production of …

Production, purification, and functional properties of microbial fibrinolytic enzymes produced by microorganism obtained from soy-based fermented foods …

M Yao, Y Yang, J Fan, C Ma, X Liu… - Critical Reviews in …, 2024 - Taylor & Francis
Abstract According to the World Health Organization, cardiovascular disease (CVD) has
become a major cause of chronic illness around the globe. It has been reported that soy …

[HTML][HTML] Food origin fibrinolytic enzyme with multiple actions

L Stephani, RR Tjandrawinata, DN Afifah, Y Lim… - HAYATI Journal of …, 2017 - Elsevier
Many health related problems such as cardiovascular diseases are associated with the
formation of excessive clot in the blood (thrombus). Approaches in cardiovascular disease …

Microbial fibrinolytic enzymes: an overview of source, production, properties, and thrombolytic activity in vivo

Y Peng, X Yang, Y Zhang - Applied microbiology and biotechnology, 2005 - Springer
Accumulation of fibrin in the blood vessels usually results in thrombosis, leading to
myocardial infarction and other cardiovascular diseases. For thrombolytic therapy, microbial …

[HTML][HTML] Cow Dung Is a Novel Feedstock for Fibrinolytic Enzyme Production from Newly Isolated Bacillus sp. IND7 and Its Application in In Vitro Clot Lysis

P Vijayaraghavan, A Arun, SGP Vincent… - Frontiers in …, 2016 - frontiersin.org
Bacterial fibrinolytic enzymes find great applications to treat and prevent cardiovascular
diseases. The novel fibrinolytic enzymes from food grade organisms are useful for …

Purification, characterization, and chemical modification of Bacillus velezensis SN-14 fibrinolytic enzyme

M Lu, Z Gao, S Xing, J Long, C Li, L He… - International Journal of …, 2021 - Elsevier
Fermented bean foods are a crucial source of fibrinolytic enzymes. The presented study
aimed to purify, characterize, and chemically modify Bacillus velezensis SN-14 fibrinolytic …

Novel Sequential Screening and Enhanced Production of Fibrinolytic Enzyme by Bacillus sp. IND12 Using Response Surface Methodology in Solid‐State …

P Vijayaraghavan, P Rajendran… - BioMed Research …, 2017 - Wiley Online Library
Fibrinolytic enzymes have wide applications in clinical and waste treatment. Bacterial
isolates were screened for fibrinolytic enzyme producing ability by skimmed milk agar plate …

Statistical media optimization for enhanced production of fibrinolytic enzyme from newly isolated Proteus penneri SP-20

SB Jhample, PK Bhagwat, PB Dandge - Biocatalysis and Agricultural …, 2015 - Elsevier
Thrombolytic enzymes are invaluable for combating cardiovascular diseases. In this study a
thorough isolation resulted, a potent fibrinolytic enzyme producer which was identified as …