Aim We performed a systematic review and network meta‐analysis (NMA) to obtain
comparative effectiveness estimates and rankings of non‐surgical interventions used to treat …

Adrenocorticotropic hormone (ACTH) and corticosteroids are the usual first-line treatment
options for infantile spasms. Despite significant differences, these agents are often lumped …

Objective: To update the 2004 American Academy of Neurology/Child Neurology Society
practice parameter on treatment of infantile spasms in children. Methods: MEDLINE and …

Aim To compare the efficacy and safety of prednisolone/prednisone and adrenocorticotropic
hormone (ACTH) in the treatment of infantile spasms using a meta‐analysis of randomized …

Objective To compare the therapeutic effectiveness of oral corticosteroids with that of
adrenocorticotrophic hormone for infantile spasms. Methods PubMed, Embase, Scopus, and …

An evidence-based update to the 2004 guidelines for the treatment of infantile spasms has
recently been published. Important new recommendations include use of low-dose …

Objective The limitations of adrenocorticotrophic hormone (ACTH) treatment for infantile
spasms (ISs), such as high costs, limited availability, and adverse effects (AEs), make it …

Background Hormonal therapy is the treatment of choice in most patients with infantile
spasms, but the optimal way to provide this therapy is unclear. Intramuscular …

Background There is ongoing debate regarding the comparative effectiveness of
adrenocorticotropic hormone and prednisolone in the treatment of infantile spasms. With a …

Objectives The manuscript serves as an update on the current management practices for
infantile spasm syndrome (ISS). It includes a detailed summary of the level of current …