By updating John Littleton's work published 15 years ago this review summarizes recent
work on pharmacodynamic aspects of acamprosate and the perspective for future …

Acamprosate is one of the few medications licensed for prevention of relapse in alcohol
dependence, and over time it has proved to be significantly, if moderately, effective, safe and …

Importance to the field: Acamprosate, marketed under the brand name Campral®,(Forest
Pharmaceuticals, Inc., Saint Louis, MO, USA; Merck Sante sas, Lyon, France) is an orally …

Acamprosate (calcium acetylhomotaurine) is an amino acid modulator that has displayed
efficacy in some clinical trials in reducing craving and promoting abstinence in alcohol …

Acamprosate has been commercially available in the USA since 2004 to treat alcohol
dependence. Its safety and efficacy have been demonstrated in a number of clinical trials …

The central nervous system-active medication acamprosate has been shown to modulate
alcohol-related behavior in both preclinical and clinical studies. Although commonly used in …

Alcoholism is one of the most prevalent substance dependence disorders in the world.
Advances in research in the neurobiological mechanisms underlying alcohol dependence …

Alcoholism is one of the most prevalent neuropsychiatric diseases, having an enormous
health and socioeconomic impact. Along with a few other medications, acamprosate …

Acamprosate is an abstinence-promoting drug widely used in the treatment of alcohol
dependence but which has a mechanism of action that has remained obscure for many …

Acamprosate is a new psychotropic drug used in the treatment of alcohol (ethanol)-
dependence. Recent studies suggest that acamprosate inhibits neuronal hyperexcitability by …