Wogonin alleviates liver injury in sepsis through Nrf2‐mediated NF‐κB signalling suppression
JM Dai, WN Guo, YZ Tan, KW Niu… - Journal of cellular …, 2021 - Wiley Online Library
Sepsis is a life‐threatening organ dysfunction syndrome, and liver is a susceptible target
organ in sepsis, because the activation of inflammatory pathways contributes to septic liver …
organ in sepsis, because the activation of inflammatory pathways contributes to septic liver …
NF-κB and Nrf2 signaling pathways contribute to wogonin-mediated inhibition of inflammation-associated colorectal carcinogenesis
J Yao, L Zhao, Q Zhao, Y Zhao, Y Sun, Y Zhang… - Cell death & …, 2014 - nature.com
The transcriptional factors nuclear factor-κB (NF-κB) and NF-E2-related factor 2 (Nrf2) have
been recently reported to have critical roles in protecting various tissues against …
been recently reported to have critical roles in protecting various tissues against …
Wenqingyin suppresses ferroptosis in the pathogenesis of sepsis-induced liver injury by activating the Nrf2-mediated signaling pathway
L Xie, C Zhou, Y Wu, X Fu, G Zhang, X Han, S Xie… - Phytomedicine, 2023 - Elsevier
Background Wenqingyin (WQY) is a classic traditional Chinese medicine formula used to
treat various inflammatory diseases. However, its protective activity against ferroptosis in the …
treat various inflammatory diseases. However, its protective activity against ferroptosis in the …
Punicalagin induces Nrf2/HO‐1 expression via upregulation of PI3K/AKT pathway and inhibits LPS‐induced oxidative stress in RAW264. 7 macrophages
X Xu, H Li, X Hou, D Li, S He, C Wan… - Mediators of …, 2015 - Wiley Online Library
Reactive oxygen species (ROS) and oxidative stress are thought to play a central role in
potentiating macrophage activation, causing excessive inflammation, tissue damage, and …
potentiating macrophage activation, causing excessive inflammation, tissue damage, and …
Curcumin alleviates lipopolysaccharide induced sepsis and liver failure by suppression of oxidative stress-related inflammation via PI3K/AKT and NF-κB related …
W Zhong, K Qian, J Xiong, K Ma, A Wang… - Biomedicine & …, 2016 - Elsevier
In many liver disorders, oxidative stress-related inflammation and apoptosis are important
pathogenic components, finally resulting in acute liver failure. Erythropoietin and its …
pathogenic components, finally resulting in acute liver failure. Erythropoietin and its …
Puerarin increases survival and protects against organ injury by suppressing NF-κB/JNK signaling in experimental sepsis
L Wang, Q Liang, A Lin, X Chen, Y Wu… - Frontiers in …, 2020 - frontiersin.org
Puerarin, an isoflavonoid rich in Radix Puerariae, has been reported to be a broadly
effective regulator in various biological processes and clinic conditions. However, the role of …
effective regulator in various biological processes and clinic conditions. However, the role of …
Wogonin suppresses inflammatory response and maintains intestinal barrier function via TLR4-MyD88-TAK1-mediated NF-κB pathway in vitro
W Wang, T Xia, X Yu - Inflammation Research, 2015 - Springer
Aims and objective Wogonin has multiple pharmacological effects, including anti-
inflammatory effects. Here, we hypothesize that wogonin can protect intestinal barrier …
inflammatory effects. Here, we hypothesize that wogonin can protect intestinal barrier …
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation
W Zhang, L Yin, X Tao, L Xu, L Zheng, X Han… - Environmental …, 2016 - Elsevier
In our previous study, the effects of dioscin against alcohol-, carbon tetrachloride-and
acetaminophen-induced liver damage have been found. However, the activity of it against …
acetaminophen-induced liver damage have been found. However, the activity of it against …
Wogonin prevents lipopolysaccharide‐induced acute lung injury and inflammation in mice via peroxisome proliferator‐activated receptor gamma‐mediated …
J Yao, D Pan, Y Zhao, L Zhao, J Sun, Y Wang… - …, 2014 - Wiley Online Library
Acute lung injury (ALI) from a variety of clinical disorders, characterized by diffuse
inflammation, is a cause of acute respiratory failure that develops in patients of all ages …
inflammation, is a cause of acute respiratory failure that develops in patients of all ages …
Oxyberberine, a novel HO-1 agonist, effectively ameliorates oxidative stress and inflammatory response in LPS/D-GalN induced acute liver injury mice via coactivating …
G Ai, X Wu, Y Dou, R Huang, L Zhong, Y Liu… - Food and Chemical …, 2022 - Elsevier
Oxyberberine (OBB), a main gut-mediated metabolite of Phellodendron chinense Cortex
(PC), exhibits prominent protective property against acute liver injury (ALI). Heme …
(PC), exhibits prominent protective property against acute liver injury (ALI). Heme …
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