Cofactors are crucial chemicals that maintain cellular redox balance and drive the cell to do
synthetic and catabolic reactions. They are involved in practically all enzymatic activities that …

NAD and NADP, a pivotal class of cofactors, which function as essential electron donors or
acceptors in all biological organisms, drive considerable catabolic and anabolic reactions …

This Research Topic is part of the Insights in Frontiers in Microbiology series launched in
2022. Cofactors such as NAD (P)+, NAD (P) H, FADH2, and ATP are frequently seen to …

Cofactors are involved in almost all enzymatic reactions in living cells, where the ratios of
NAD (P) H/NAD (P)+ plays a significant role in microbial metabolism. The instability of NAD …

Cofactors, such as adenosine triphosphate, nicotinamide adenine dinucleotide, and
coenzyme A, are involved in nearly 50% of enzymatic reactions and widely used in …

What does it take to convert a living organism into a truly productive biofactory? Apart from
optimizing biosynthesis pathways as standalone units, a successful bioengineering …

Redox balance plays an important role in the production of enzymes, pharmaceuticals, and
chemicals. To meet the demands of industrial production, it is desirable that microbes …

Cofactor engineering has been long identified as a valuable tool for metabolic engineering.
Besides interventions targeting the pools of redox cofactors, many studies addressed the …

Optimizing the overall NADPH turnover is one of the key challenges in various value-added
biochemical syntheses. In this work, we first analyzed the NADPH regeneration potentials of …

Microorganisms are able to produce a wide range of valuable chemicals and materials, and
microbial fermentation is widely used as an alternative route for the production of chemicals …